Recombinant Human ATXN10 Protein, MYC/DDK-tagged

• Cat.No.: ATXN10-3037H
• Product Overview: Recombinant Human ATXN10 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 46.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ATXN10 ataxin 10 [ Homo sapiens ]
• Official Symbol: ATXN10
• Synonyms: E46L; HUMEEP; SCA10
• Gene ID: 25814
• mRNA Refseq: NM_001167621
• Protein Refseq: NP_001161093
• MIM: 611150
• UniProt ID: Q9UBB4