Recombinant Human ATXN10 Protein, MYC/DDK-tagged
Cat.No. : | ATXN10-3037H |
Product Overview : | Recombinant Human ATXN10 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 46.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | ATXN10 ataxin 10 [ Homo sapiens ] |
Official Symbol : | ATXN10 |
Synonyms : | E46L; HUMEEP; SCA10 |
Gene ID : | 25814 |
mRNA Refseq : | NM_001167621 |
Protein Refseq : | NP_001161093 |
MIM : | 611150 |
UniProt ID : | Q9UBB4 |
Products Types
◆ Recombinant Protein | ||
ATXN10-79C | Recombinant Cynomolgus Monkey ATXN10 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATXN10-900M | Recombinant Mouse ATXN10 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATXN10-557R | Recombinant Rat ATXN10 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATXN10-306R | Recombinant Rhesus Macaque ATXN10 Protein, His (Fc)-Avi-tagged | +Inquiry |
Atxn10-1783M | Recombinant Mouse Atxn10 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
ATXN10-51HCL | Recombinant Human ATXN10 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionThe research of ATXN10 protein mainly focuses on understanding its functional regulation mechanism, its relationship with the pathogenesis of SCA10, and the search for therapeutic methods for SCA10. At present, several important advances have been made regarding the function of ATXN10 protein and the pathogenesis of SCA10.
ATXN10 protein is involved in the regulation of a variety of neural cell functions, including transcription regulation, RNA processing, cell cycle regulation, etc. It plays an important role in the development and functional maintenance of the nervous system.
The function of ATXN10 protein is regulated by a variety of regulatory mechanisms, including the binding of transcriptional regulators and post-translational modifications. These regulatory mechanisms ensure the adaptability and stability of ATXN10 protein.
Yes, the ATXN10 protein interacts with multiple proteins to form complexes involved in the regulation of a variety of cellular functions. For example, ATXN10 interacts with TATA box binding protein (TBP) and participates in transcriptional regulation.
In addition to SCA10, ATXN10 protein has been implicated in the development and progression of other neurological diseases. For example, it may be associated with the pathogenesis of neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease. However, further studies are needed to confirm these associations.
The protein is associated with spinocerebellar ataxia type 10 (SCA10). SCA10 is an inherited neurodegenerative disorder characterized by dysfunction of the cerebellum and spinal cord leading to ataxia and other neurological symptoms.
Customer Reviews (3)
Write a reviewIt's the most biologically active protein I've ever seen, and the purity of its production is impressive.
This production process of Atxn10 uses renewable resources as raw materials, making the production process more environmentally friendly and sustainable.
The short half-life and high clearance of Atxn10 make them more safe and effective in clinical application.
Ask a Question for All ATXN10 Products
Required fields are marked with *
My Review for All ATXN10 Products
Required fields are marked with *
Inquiry Basket