Recombinant Human AURKB Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: AURKB-5410H
• Product Overview: AURKB MS Standard C13 and N15-labeled recombinant protein (NP_004208) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 39.1 kDa
• AA Sequence: MAQKENSYPWPYGRQTAPSGLSTLP QRVLRKEPVTPSALVLMSRSNVQPT AAPGQKVMENSSGTPDILTRHFTID DFEIGRPLGKGKFGNVYLAREKKSH FIVALKVLFKSQIEKEGVEHQLRRE IEIQAHLHHPNILRLYNYFYDRRRI YLILEYAPRGELYKELQKSCTFDEQ RTATIMEELADALMYCHGKKVIHRD IKPENLLLGLKGELKIADFGWSVHA PSLRRKTMCGTLDYLPPEMIEGRMH NEKVDLWCIGVLCYELLVGNPPFES ASHNETYRRIVKVDLKFPASVPTGA QDLISKLLRHNPSERLPLAQVSAHP WVRANSRRVLPPSALQSVATRTRPL EQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: AURKB aurora kinase B [ Homo sapiens (human) ]
• Official Symbol: AURKB
• Synonyms: AURKB; aurora kinase B; serine/threonine kinase 12, STK12; Aik2; AIM 1; ARK2; AurB; aurora 1; aurora B; IPL1; PPP1R48; protein phosphatase 1; regulatory subunit 48; STK5; ARK-2; STK-1; aurora-1; aurora-B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora-related kinase 2; serine/threonine kinase 12; aurora/IPL1-related kinase 2; serine/threonine-protein kinase 5; serine/threonine-protein kinase 12; serine/threonine-protein kinase aurora-B; protein phosphatase 1, regulatory subunit 48; aurora- and Ipl1-like midbody-associated protein 1; AIK2; AIM1; AIM-1; STK12; aurkb-sv1; aurkb-sv2
• Gene ID: 9212
• mRNA Refseq: NM_004217
• Protein Refseq: NP_004208
• MIM: 604970
• UniProt ID: Q96GD4