Recombinant Human AURKC Protein (S2-S309), Tag Free
Cat.No. : | AURKC-1114H |
Product Overview : | Recombinant Human GG-AURC(S2-S309 end) Protein was expressed in Insect cell. |
- Specification
- Gene Information
- Related Products
Description : | Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. AURKC phosphorylates the CPC complex subunits BIRC5/survivin and INCENP leading to increased AURKC activity. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'. |
Source : | Insect cell |
Species : | Human |
Tag : | No tag |
Form : | Liquid |
Protein Length : | S2-S309 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | AURKC aurora kinase C [ Homo sapiens (human) ] |
Official Symbol : | AURKC |
Synonyms : | AURKC; aurora kinase C; serine/threonine kinase 13 (aurora/IPL1 like), STK13; ARK3; AurC; ARK-3; aurora 3; aurora-related kinase 3; aurora/IPL1/EG2 protein 2; aurora/IPL1-related kinase 3; serine/threonine-protein kinase 13; serine/threonine-protein kinase aurora-C; serine/threonine kinase 13 (aurora/IPL1-like); AIE2; AIK3; SPGF5; STK13; aurora-C; |
Gene ID : | 6795 |
mRNA Refseq : | NM_001015878 |
Protein Refseq : | NP_001015878 |
MIM : | 603495 |
UniProt ID : | Q9UQB9 |
Products Types
◆ Recombinant Protein | ||
Aurkc-531M | Recombinant Mouse Aurkc Protein, His-tagged | +Inquiry |
AURKC-530H | Recombinant Human AURKC Protein, His-tagged | +Inquiry |
AURKC-1115H | Recombinant Human AURKC Protein (S2-S309), GST tagged | +Inquiry |
Aurkc-532R | Recombinant Rat Aurkc Protein, His-tagged | +Inquiry |
AURKC-1039H | Recombinant Human AURKC protein, GST-tagged | +Inquiry |
◆ Lysates | ||
AURKC-8559HCL | Recombinant Human AURKC 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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