Recombinant Human AXL Protein, DYKDDDDK-tagged

• Cat.No.: AXL-088H
• Product Overview: Recombinant protein of the extracellular domain (Ala26-Trp451) of homo sapiens AXL receptor tyrosine kinase (AXL), transcript variant 1 (NM_021913), with a polyhistidine tag was expressed in human cells.

Specification

• Description: The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.
• Source: Human cells
• Species: Human
• Tag: DYKDDDDK
• Molecular Mass: 50 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/μg of protein (< 1 EU /μg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
• Storage Buffer: Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives

Gene Information

• Gene Name: AXL AXL receptor tyrosine kinase [ Homo sapiens (human) ]
• Official Symbol: AXL
• Synonyms: AXL; AXL receptor tyrosine kinase; ARK; UFO; JTK11; Tyro7; tyrosine-protein kinase receptor UFO; AXL oncogene; AXL transforming sequence/gene; EC 2.7.10.1
• Gene ID: 558
• mRNA Refseq: NM_021913
• Protein Refseq: NP_068713
• MIM: 109135
• UniProt ID: P30530