Recombinant Human AXL protein, GST-tagged

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Recombinant Human AXL protein, GST-tagged

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Cat.No. : AXL-1049H
Product Overview : Human AXL full-length ORF ( AAH32229.1, 1 a.a. - 894 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 124.8 kDa
AA Sequence : MAWRCPRMGRVPLAW CLALCGWACMAPRGT QAEESPFVGNPGNIT GARGLTGTLRCQLQV QGEPPEVHWLRDGQI LELADSTQTQVPLGE DEQDDWIVVSQLRIT SLQLSDTGQYQCLVF LGHQTFVSQPGYVGL EGLPYFLEEPEDRTV AANTPFNLSCQAQGP PEPVDLLWLQDAVPL ATAPGHGPQRSLHVP GLNKTSSFSCEAHNA KGVTTSRTATITVLP QQPRNLHLVSRQPTE LEVAWTPGLSGIYPL THCTLQAVLSDDGMG IQAGEPDPPEEPLTS QASVPPHQLRLGSLH PHTPYHIRVACTSSQ GPSSWTHWLPVETPE GVPLGPPENISATRN GSQAFVHWQEPRAPL QGTLLGYRLAYQGQD TPEVLMDIGLRQEVT LELQGDGSVSNLTVC VAAYTAAGDGPWSLP VPLEAWRPGQAQPVH QLVKEPSTPAFSWPW WYVLLGAVVAAACVL ILALFLVHRRKKETR YGEVFEPTVERGELV VRYRVRKSYSRRTTE ATLNSLGISEELKEK LRDVMVDRHKVALGK TLGEGEFGAVMEGQL NQDDSILKVAVKTMK IAICTRSELEDFLSE AVCMKEFDHPNVMRL IGVCFQGSERESFPA PVVILPFMKHGDLHS FLLYSRLGDQPVYLP TQMLVKFMADIASGM EYLSTKRFIHRDLAA RNCMLNENMSVCVAD FGLSKKIYNGDYYRQ GRIAKMPVKWIAIES LADRVYTSKSDVWSF GVTMWEIATRGQTPY PGVENSEIYDYLRRG NRLKQPADCLDGLYA LMSRCWELNPQDRPS FTELREDLENTLKAL PPAQEPDEILYVNMD EGGGYPEPPGAAGGA DPPTQPDPKDSCSCL TAAEVHPAGRYVLCP STTPSPAQPADRGSP AAPGQEDGA
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Figure :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : AXL AXL receptor tyrosine kinase [ Homo sapiens ]
Official Symbol : AXL
Synonyms : AXL; AXL receptor tyrosine kinase; tyrosine-protein kinase receptor UFO; JTK11; UFO; AXL oncogene; oncogene AXL; AXL transforming sequence/gene;
Gene ID : 558
mRNA Refseq : NM_001699
Protein Refseq : NP_001690
MIM : 109135
UniProt ID : P30530

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