Recombinant Human AXL protein, His-Avi-tagged

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Recombinant Human AXL protein, His-Avi-tagged

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Cat.No. : AXL-585H
Product Overview : Recombinant Human Axl Protein is expressed from Expi293 with a His and Avi Tag at the C-terminal. It contains Ala26-Pro 449.
Description : Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.
Source : HEK293
Species : Human
Tag : His-Avi
Form : Supplied as 0.22um filtered solution in PBS (pH 7.4).
Molecular Mass : The protein has a predicted MW of 48.7 kDa.Due to glycosylation, the protein migrates to 70-80 KDa based on Bis-Tris PAGE result.
Protein length : It contains Ala26-Pro 449.
Endotoxin : Less than 1 EU per ug by the LAL method.
Purity : > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Tris-Bis PAGE :

HPLC data :

Gene Name : AXL AXL receptor tyrosine kinase [ Homo sapiens ]
Official Symbol : AXL
Synonyms : Axl; UFO; AXL oncogene; AXL
Gene ID : 558
mRNA Refseq : NM_001699
Protein Refseq : NP_001690
MIM : 109135
UniProt ID : P30530

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