Recombinant Human BCAR1 Protein, GST-tagged

• Cat.No.: BCAR1-120H
• Product Overview: Human BCAR1 full-length ORF ( AAH62556.1, 1 a.a. - 870 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion (Sawada et al., 2006 [PubMed 17129785]).
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 119.8 kDa
• AA Sequence: MNHLNVLAKALYDNVAESPDELSFR KGDIMTVLEQDTQGLDGWWLCSLHG RQGIVPGNRLKILVGMYDKKPAGPG SGPPATPAQPQPGLHAPAPPASQYT PMLPNTYQPQPDSVYLVPTPSKAQQ GLYQVPGPSPQFQSPPAKQTSTFSK QTPHHPFPNPATDLYQVPPGPGGPA QDIYQVPPSAGMGHDIYQVPPSMDT RSWEGTKPPAKVVVPTRVGQGYVYE AAQPEQDEYDIPRHLLAPGPQDIYD VPPVRGLLPSQYGQEVYDTPPMAVK GPNGRDPLLEVYDVPPSVEKGLPPS NHHAVYDVPPSVSKDVPDGPLLREE TYDVPPAFAKAKPFDPARTPLVLAA PPPDSPPAEDVYDVPPPAPDLYDVP PGLRRPGPGTLYDVPRERVLPPEVA DGGVVDSGVYAVPPPAEREAPAEGK RLSASSTGSTRSSQSASSLEVAGPG REPLELEVAVEALARLQQGVSATVA HLLDLAGSAGATGSWRSPSEPQEPL VQDLQAAVAAVQSAVHELLEFARSA VGNAAHTSDRALHAKLSRQLQKMED VHQTLVAHGQALDAGRGGSGATLED LDRLVACSRAVPEDAKQLASFLHGN ASLLFRRTKATAPGPEGGGTLHPNP TDKTSSIQSRPLPSPPKFTSQDSPD GQYENSEGGWMEDYDYVHLQGKEEF EKTQKELLEKGSITRQGKSQLELQQ LKQFERLEQEVSRPIDHDLANWTPA QPLAPGRTGGLGPSDRQLLLFYLEQ CEANLTTLTNAVDAFFTAVATNQPP KIFVAHSKFVILSAHKLVFIGDTLS RQAKAADVRSQVTHYSNLLCDLLRG IVATTKAAALQYPSPSAAQDMVERV KELGHSTQQFRRVLGQLAAA
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: BCAR1 breast cancer anti-estrogen resistance 1 [ Homo sapiens ]
• Official Symbol: BCAR1
• Synonyms: BCAR1; breast cancer anti-estrogen resistance 1; breast cancer anti-estrogen resistance protein 1; CAS; Cas scaffolding protein family member 1; CASS1; Crk associated substrate; Crkas; P130Cas; Crk-associated substrate p130Cas; CAS1; CRKAS; FLJ12176; FLJ45059
• Gene ID: 9564
• mRNA Refseq: NM_001170714
• Protein Refseq: NP_001164185
• MIM: 602941
• UniProt ID: P56945