Description : |
This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. |
Source : |
Wheat Germ |
Species : |
Human |
Tag : |
GST |
Form : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : |
90.7 kDa |
AA Sequence : |
MGNQMSVPQRVEDQENEPEAETYKD NASALNGVPVVVSTHTVQHLEEVDL GISVKTDNVATSSPETTEISAVADA NGKNLGKEAKPEAPAAKSRFFLMLS RPVPGRTGDQAADSSLGSVKLDVSS NKAPANKDPSESWTLPVAAGPGQDT DKTPGHAPAQDKALSAARDPTLLPP ETGGAGGEAPSKPKDSSFFDKFFKL DKGQEKVPGDSQQEAKRAEHQDKVD EVPGLSGQSDDVPAGKDIVDGKEKE GQELGTADCSVPGDPEGLETAKDDS QAAAIAENNNSIMSFFKTLVSPNKA ETKKDPEDTGAEKSPTTSADLKSDK ANFTSQETQGAGKNSKGCNPSGHTQ SVTTPEPAKEGTKEKSGPTSLPLGK LFWKKSVKEDSVPTGAEENVVCESP VEIIKSKEVESALQTVDLNEGDAAP EPTEAKLKREESKPRTSLMAFLRQM SVKGDGGITHSEEINGKDSSCQTSD STEKTITPPEPEPTGAPQKGKEGSS KDKKSAAEMNKQKSNKQEAKEPAQC TEQATVDTNSLQNGDKLQKRPEKRQ QSLGGFFKGLGPKRMLDAQVQTDPV SIGPVGKSK |
Notes : |
Best use within three months from the date of receipt of this protein. |
Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |