Recombinant Human BCL7A Protein, MYC/DDK-tagged, C13 and N15-labeled

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Recombinant Human BCL7A Protein, MYC/DDK-tagged, C13 and N15-labeled

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Cat.No. : BCL7A-051H
Product Overview : BCL7A MS Standard C13 and N15-labeled recombinant protein (NP_001019979) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 22.8 kDa
AA Sequence : MSGRSVRAET RSRAKDDIKR VMAAIEKVRK WEKKWVTVGD TSLRIYKWVP VTEPKVDDKN KNKKKGKDEK CGSEVTTPEN SSSPGMMDMH DDNSNQSSIA DASPIKQENS SNSSPAPEPN SAVPSDGTEA KVDEAQADGK EHPGAEDASD EQNSQSSMEH SMNSSEKVDR QPSGDSGLAA ETSAISQDLE GVPPSKKMKL EASQQNSEEM TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : BCL7A BAF chromatin remodeling complex subunit BCL7A [ Homo sapiens (human) ]
Official Symbol : BCL7A
Synonyms : BCL7A; BAF chromatin remodeling complex subunit BCL7A; BCL7; B-cell CLL/lymphoma 7 protein family member A; B-cell CLL/lymphoma 7A; B-cell CLL/lymphoma-7; BCL tumor suppressor 7A; BCL7A, BAF complex component
Gene ID : 605
mRNA Refseq : NM_001024808
Protein Refseq : NP_001019979
MIM : 601406
UniProt ID : Q4VC05

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