Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human BDNF Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : BDNF-3171H
Product Overview : BDNF MS Standard C13 and N15-labeled recombinant protein (NP_733930) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 25.7 kDa
AA Sequence : MQSREEEWFHQVRRVMTILFLTMVI SYFGCMKAAPMKEANIRGQGGLAYP GVRTHGTLESVNGPKAGSRGLTSLA DTFEHVIEELLDEDQKVRPNEENNK DADLYTSRVMLSSQVPLEPPLLFLL EEYKNYLDAANMSMRVRRHSDPARR GELSVCDSISEWVTAADKKTAVDMS GGTVTVLEKVPVSKGQLKQYFYETK CNPMGYTKEGCRGIDKRHWNSQCRT TQSYVRALTMDSKKRIGWRFIRIDT SCVCTLTIKRGRTRTRPLEQKLISE EDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : BDNF brain-derived neurotrophic factor [ Homo sapiens (human) ]
Official Symbol : BDNF
Synonyms : BDNF; brain-derived neurotrophic factor; neurotrophin; abrineurin; MGC34632;
Gene ID : 627
mRNA Refseq : NM_170734
Protein Refseq : NP_733930
MIM : 113505
UniProt ID : P23560

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
How is BDNF measured in clinical settings? 10/26/2021

BDNF levels can be measured through blood tests or cerebrospinal fluid analysis, providing insights into the protein's concentration in the body.

What neurological disorders are associated with BDNF deficiency? 10/03/2018

BDNF deficiency has been linked to conditions such as Alzheimer's disease, Parkinson's disease, and depression.

Are there medications that target BDNF for clinical use? 08/02/2018

While there are no direct BDNF medications, certain drugs and treatments aim to enhance BDNF levels indirectly, offering potential therapeutic benefits.

How does physical exercise influence BDNF levels, and what implications does this have for clinical applications? 06/24/2017

Physical exercise has been shown to increase BDNF production, suggesting that exercise could be used as a non-pharmacological intervention to support neurological health.

What role does BDNF play in synaptic plasticity, and how does it impact learning and memory? 01/28/2016

BDNF is crucial for synaptic plasticity, influencing the strength and efficacy of connections between neurons, which is vital for learning and memory processes.

Customer Reviews (3)

Write a review
Reviews
12/31/2022

    The BDNF protein is carefully characterized, and its functional properties are well-documented.

    04/08/2021

      With its high purity and bioactivity, BDNF protein ensures reliable and consistent results in a wide range of experimental applications.

      11/27/2017

        The BDNF protein is of exceptional quality and is perfectly suited to meet the experimental needs of researchers.

        Ask a Question for All BDNF Products

        Required fields are marked with *

        My Review for All BDNF Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends