Recombinant Human BDNF Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | BDNF-3171H |
Product Overview : | BDNF MS Standard C13 and N15-labeled recombinant protein (NP_733930) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 25.7 kDa |
AA Sequence : | MQSREEEWFHQVRRVMTILFLTMVI SYFGCMKAAPMKEANIRGQGGLAYP GVRTHGTLESVNGPKAGSRGLTSLA DTFEHVIEELLDEDQKVRPNEENNK DADLYTSRVMLSSQVPLEPPLLFLL EEYKNYLDAANMSMRVRRHSDPARR GELSVCDSISEWVTAADKKTAVDMS GGTVTVLEKVPVSKGQLKQYFYETK CNPMGYTKEGCRGIDKRHWNSQCRT TQSYVRALTMDSKKRIGWRFIRIDT SCVCTLTIKRGRTRTRPLEQKLISE EDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | BDNF brain-derived neurotrophic factor [ Homo sapiens (human) ] |
Official Symbol : | BDNF |
Synonyms : | BDNF; brain-derived neurotrophic factor; neurotrophin; abrineurin; MGC34632; |
Gene ID : | 627 |
mRNA Refseq : | NM_170734 |
Protein Refseq : | NP_733930 |
MIM : | 113505 |
UniProt ID : | P23560 |
Products Types
◆ Recombinant Protein | ||
BDNF-2466H | Recombinant Human BDNF Protein, MYC/DDK-tagged | +Inquiry |
BDNF-298B | Active Recombinant Human BDNF Protein | +Inquiry |
BDNF-007H | Active Recombinant Human BDNF Protein | +Inquiry |
BDNF-01H | Recombinant Active Human BDNF Protein, His-tagged | +Inquiry |
Bdnf-310M | Recombinant Mouse Bdnf Protein, His-tagged | +Inquiry |
◆ Lysates | ||
BDNF-001MCL | Recombinant Mouse BDNF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionBDNF levels can be measured through blood tests or cerebrospinal fluid analysis, providing insights into the protein's concentration in the body.
BDNF deficiency has been linked to conditions such as Alzheimer's disease, Parkinson's disease, and depression.
While there are no direct BDNF medications, certain drugs and treatments aim to enhance BDNF levels indirectly, offering potential therapeutic benefits.
Physical exercise has been shown to increase BDNF production, suggesting that exercise could be used as a non-pharmacological intervention to support neurological health.
BDNF is crucial for synaptic plasticity, influencing the strength and efficacy of connections between neurons, which is vital for learning and memory processes.
Customer Reviews (3)
Write a reviewThe BDNF protein is carefully characterized, and its functional properties are well-documented.
With its high purity and bioactivity, BDNF protein ensures reliable and consistent results in a wide range of experimental applications.
The BDNF protein is of exceptional quality and is perfectly suited to meet the experimental needs of researchers.
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