| Description : |
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
45.9 kDa |
| AA Sequence : |
MSERRVVVDLPTSASSSMPLQRRRA SFRGPRSSSSLESPPASRTNAMSGL VRAPGVYVGTAPSGCIGGLGARVTR RALGISSVFLQGLRSSGLATVPAPG LERDHGAVEDLGGCLVEYMAKVHAL EQVSQELETQLRMHLESKATRSGNW GALRASWASSCQQVGEAVLENARLM LQTETIQAGADDFKERYENEQPFRK AAEEEINSLYKVIDEANLTKMDLES QIESLKEELGSLSRNYEEDVKLLHK QLAGCELEQMDAPIGTGLDDILETI RIQWERDVEKNRVEAGALLQAKQQA EVAHMSQTQEEKLAAALRVELHNTS CQVQSLQAETESLRALKRGLENTLH DAKHWHDMELQNLGAVVGRLEAELR EIRAEAEQQQQERAHLLARKCQLQK DVASYHALLDREESGTRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
