Recombinant Human BHMT2 Protein, MYC/DDK-tagged, C13 and N15-labeled

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Recombinant Human BHMT2 Protein, MYC/DDK-tagged, C13 and N15-labeled

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Cat.No. : BHMT2-346H
Product Overview : BHMT2 MS Standard C13 and N15-labeled recombinant protein (NP_060084) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 40.4 kDa
AA Sequence : MAPAGRPGAK KGILERLESG EVVIGDGSFL ITLEKRGYVK AGLWTPEAVI EHPDAVRQLH MEFLRAGSNV MQTFTFSASE DNMESKWEDV NAAACDLARE VAGKGDALVA GGICQTSIYK YQKDEARIKK LFRQQLEVFA WKNVDFLIAE YFEHVEEAVW AVEVLKESDR PVAVTMCIGP EGDMHDITPG ECAVRLVKAG ASIVGVNCRF GPDTSLKTME LMKEGLEWAG LKAHLMVQPL GFHAPDCGKE GFVDLPEYPF GLESRVATRW DIQKYAREAY NLGVRYIGGC CGFEPYHIRA IAEELAPERG FLPPASEKHG SWGSGLDMHT KPWIRARARR EYWENLLPAS GRPFCPSLSK PDFTRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : BHMT2 betaine--homocysteine S-methyltransferase 2 [ Homo sapiens (human) ]
Official Symbol : BHMT2
Synonyms : BHMT2; betaine--homocysteine S-methyltransferase 2; S-methylmethionine--homocysteine S-methyltransferase BHMT2; SMM-hcy methyltransferase; betaine-homocysteine methyltransferase 2; FLJ20001;
Gene ID : 23743
mRNA Refseq : NM_017614
Protein Refseq : NP_060084
MIM : 605932
UniProt ID : Q9H2M3

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