Recombinant Human BIRC7 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human BIRC7 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : BIRC7-4174H
Product Overview : BIRC7 MS Standard C13 and N15-labeled recombinant protein (NP_647478) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 32.8 kDa
AA Sequence : MGPKDSAKCL HRGPQPSHWA AGDGPTQERC GPRSLGSPVL GLDTCRAWDH VDGQILGQLR PLTEEEEEEG AGATLSRGPA FPGMGSEELR LASFYDWPLT AEVPPELLAA AGFFHTGHQD KVRCFFCYGG LQSWKRGDDP WTEHAKWFPS CQFLLRSKGR DFVHSVQETH SQLLGSWDPW EEPEDAAPVA PSVPASGYPE LPTPRREVQS ESAQEPGGVS PAQAQRAWWV LEPPGARDVE AQLRRLQEER TCKVCLDRAV SIVFVPCGHL VCAECAPGLQ LCPICRAPVR SRVRTFLSTR TRPLEQKLIS EEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : BIRC7 baculoviral IAP repeat containing 7 [ Homo sapiens (human) ]
Official Symbol : BIRC7
Synonyms : BIRC7; baculoviral IAP repeat containing 7; baculoviral IAP repeat-containing protein 7; KIAP; kidney inhibitor of apoptosis protein; livin; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein; ML IAP; mliap; RNF50; RING finger protein 50; LIVIN; MLIAP; ML-IAP;
Gene ID : 79444
mRNA Refseq : NM_139317
Protein Refseq : NP_647478
MIM : 605737
UniProt ID : Q96CA5

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