| Description : |
Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Form : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Molecular Mass : |
79 kDa |
| AA Sequence : |
MSSSGLNSEKVAALIQKLNSDPQFV LAQNVGTTHDLLDICLKRATVQRAQ HVFQHAVPQEGKPITNQKSSGRCWI FSCLNVMRLPFMKKLNIEEFEFSQS YLFFWDKVERCYFFLSAFVDTAQRK EPEDGRLVQFLLMNPANDGGQWDML VNIVEKYGVIPKKCFPESYTTEATR RMNDILNHKMREFCIRLRNLVHSGA TKGEISATQDVMMEEIFRVVCICLG NPPETFTWEYRDKDKNYQKIGPITP LEFYREHVKPLFNMEDKICLVNDPR PQHKYNKLYTVEYLSNMVGGRKTLY NNQPIDFLKKMVAASIKDGEAVWFG CDVGKHFNSKLGLSDMNLYDHELVF GVSLKNMNKAERLTFGESLMTHAMT FTAVSEKDDQDGAFTKWRVENSWGE DHGHKGYLCMTDEWFSEYVYEVVVD RKHVPEEVLAVLEQEPIILPAWDPM GALAE |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
