Recombinant Human BMF Protein, GST-tagged

• Cat.No.: BMF-255H
• Product Overview: Human BMF full-length ORF ( AAH69505.1, 1 a.a. - 184 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 46.9 kDa
• AA Sequence: MEPSQCVEELEDDVFQPEDGEPVTQ PGSLLSADLFAQSLLDCPLSRLQLF PLTHCCGPGLRPTSQEDKATQTLSP ASPSPGVMLPCGVTEEPQRLFYGNA GYRLPLPASFPAVLPIGEQPPEGQW QHQAEVQIARKLQCIADQFHRLHVQ QHQQNQNRVWWQILLFLHNLALNGE ENRNGAGPR
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: BMF Bcl2 modifying factor [ Homo sapiens ]
• Official Symbol: BMF
• Synonyms: BMF; Bcl2 modifying factor; bcl-2-modifying factor; FLJ00065
• Gene ID: 90427
• mRNA Refseq: NM_001003940
• Protein Refseq: NP_001003940
• MIM: 606266
• UniProt ID: Q96LC9