| Description : |
This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
129 kDa |
| AA Sequence : |
MKKFSRMPKSEGGSGGGAAGGGAGG AGAGAGCGSGGSSVGVRVFAVGRHQ VTLEESLAEGGFSTVFLVRTHGGIR CALKRMYVNNMPDLNVCKREITIMK ELSGHKNIVGYLDCAVNSISDNVWE VLILMEYCRAGQVVNQMNKKLQTGF TEPEVLQIFCDTCEAVARLHQCKTP IIHRDLKVENILLNDGGNYVLCDFG SATNKFLNPQKDGVNVVEEEIKKYT TLSYRAPEMINLYGGKPITTKADIW ALGCLLYKLCFFTLPFGESQVAICD GNFTIPDNSRYSRNIHCLIRFMLEP DPEHRPDIFQVSYFAFKFAKKDCPV SNINNSSIPSALPEPMTASEAAARK SQIKARITDTIGPTETSIAPRQRPK ANSATTATPSVLTIQSSATPVKVLA PGEFGNHRPKGALRPGNGPEILLGQ GPPQQPPQQHRVLQQLQQGDWRLQQ LHLQHRHPHQQQQQQQQQQQQQQQQ QQQQQQQQQQQHHHHHHHHLLQDAY MQQYQHATQQQQMLQQQFLMHSVYQ PQPSASQYPTMMPQYQQAFFQQQML AQHQPSQQQASPEYLTSPQEFSPAL VSYTSSLPAQVGTIMDSSYSANRSV ADKEAIANFTNQKNISNPPDMSGWN PFGEDNFSKLTEEELLDREFDLLRS NRLEERASSDKNVDSLSAPHNHPPE DPFGSVPFISHSGSPEKKAEHSSIN QENGTANPIKNGKTSPASKDQRTGK KTSVQGQVQKGNDESESDFESDPPS PKSSEEEEQDDEEVLQGEQGDFNDD DTEPENLGHRPLLMDSEDEEEEEKH SSDSDYEQAKAKYSDMSSVYRDRSG SGPTQDLNTILLTSAQLSSDVAVET PKQEFDVFGAVPFFAVRAQQPQQEK NEKNLPQHRFPAAGLEQEEFDVFTK APFSKKVNVQECHAVGPEAHTIPGY PKSVDVFGSTPFQPFLTSTSKSESN EDLFGLVPFDEITGSQQQKVKQRSL QKLSSRQRRTKQDMSKSNGKRHHGT PTSTKKTLKPTYRTPERARRHKKVG RRDSQSSNEFLTISDSKENISVALT DGKDRGNVLQPEESLLDPFGAKPFH SPDLSWHPPHQGLSDIRADHNTVLP GRPRQNSLHGSFHSADVLKMDDFGA VPFTELVVQSITPHQSQQSQPVELD PFGAAPFPSKQTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
