Recombinant Human BTNL2 Protein, Fc-tagged
Cat.No. : | BTNL2-23H |
Product Overview : | Recombinant Human BTNL2 Protein, fused to Fc-tag, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer. |
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | PBS, pH7.4 |
Molecular Mass : | 74 kDa |
AA Sequence : | MHSSALLCCLVLLTGVRAKQSEDFR VIGPAHPILAGVGEDALLTCQLLPK RTTMHVEVRWYRSEPSTPVFVHRDG VEVTEMQMEEYRGWVEWIENGIAKG NVALKIHNIQPSDNGQYWCHFQDGN YCGETSLLLKVAGLGSAPSIHMEGP GESGVQLVCTARGWFPEPQVYWEDI RGEKLLAVSEHRIQDKDGLFYAEAT LVVRNASAESVSCLVHNPVLTEEKG SVISLPEKLQTELASLKVNGPSQPI LVRVGEDIQLTCYLSPKANAQSMEV RWDRSHRYPAVHVYMDGDHVAGEQM AEYRGRTVLVSDAIDEGRLTLQILS ARPSDDGQYRCLFEKDDVYQEASLD LKVVSLGSSPLITVEGQEDGEMQPM CSSDGWFPQPHVPWRDMEGKTIPSS SQALTQGSHGLFHVQTLLRVTNISA VDVTCSISIPFLGEEKIATFSLSGW GGGGSGGGGSGGGGSDKTHTCPPCP APELLGGPSVFLFPPKPKDTLMISR TPEVTCVVVDVSHEDPEVKFNWYVD GVEVHNAKTKPREEQYNSTYRVVSV LTVLHQDWLNGKEYKCKVSNKALPA PIEKTISKAKGQPREPQVYTLPPSR DELTKNQVSLTCLVKGFYPSDIAVE WESNGQPENNYKTTPPVLDSDGSFF LYSKLTVDKSRWQQGNVFSCSVMHE ALHNHYTQKSLSLSPGK |
Purity : | >90% |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Concentration : | 0.07mg/ml |
Gene Name : | BTNL2 butyrophilin like 2 [ Homo sapiens (human) ] |
Official Symbol : | BTNL2 |
Synonyms : | SS2; BTN7; BTL-II; HSBLMHC1 |
Gene ID : | 56244 |
mRNA Refseq : | NM_001304561 |
Protein Refseq : | NP_001291490 |
MIM : | 606000 |
UniProt ID : | Q9UIR0 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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