Recombinant Human CABP1 Protein, GST-Tagged

• Cat.No.: CABP1-0258H
• Product Overview: Human CABP1 full-length ORF (AAH15006, 1 a.a. - 304 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Calcium binding proteins are an important component of calcium mediated cellular signal transduction. This gene encodes a protein that belongs to a subfamily of calcium binding proteins which share similarity to calmodulin. The protein encoded by this gene regulates the gating of voltage-gated calcium ion channels. This protein inhibits calcium-dependent inactivation and supports calcium-dependent facilitation of ion channels containing voltage-dependent L-type calcium channel subunit alpha-1C. This protein also regulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors, P/Q-type voltage-gated calcium channels, and transient receptor potential channel TRPC5. This gene is predominantly expressed in retina and brain. Alternative splicing results in multiple transcript variants encoding disinct isoforms. [provided by RefSeq, Jul 2012]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 59.18 kDa
• AA Sequence: MCQCVRVCVCVCACATQRASHSALP GTTISVKDWRLCLLDQFDACARSGL SEPRSLTLRVPSCGKPLPGPGARLG REVTPCLSFAFAWCWLKMCQEEQTS YMVVQTSEEGLAADAELPGPLLMLA QNCAVMHNLLGPACIFLRKGFAENR QPDRSLRPEEIEELREAFREFDKDK DGYINCRDLGNCMRTMGYMPTEMEL IELSQQINMNLGGHVDFDDFVELMG PKLLAETADMIGVKELRDAFREFDT NGDGEISTSELREAMRKLLGHQVGH RDIEEIIRDVDLNGDGRVDFEEFVR MMSR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CABP1 calcium binding protein 1; calbrain [ Homo sapiens ]
• Official Symbol: CABP1
• Synonyms: CABP1; calcium binding protein 1; calbrain
• Gene ID: 9478
• mRNA Refseq: NM_001033677
• Protein Refseq: NP_001028849
• MIM: 605563
• UniProt ID: Q9NZU7