| Species : | Mouse | 
                                
                                    | Source : | HEK293 | 
                                
                                    | Tag : | DDK&Myc | 
                                
                                    | Description : | Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but has an opposite effect on channel function. Suppresses the calcium-dependent inactivation of CACNA1D. Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration. Required for the normal transfer of light signals through the retina. | 
                                
                                    | Molecular Mass : | 25.9 kDa | 
                                
                                    | Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining | 
                                
                                    | Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. | 
                                
                                    | Storage : | Store at -80 centigrade after receiving vials. | 
                                
                                    | Concentration : | >50 μg/mL as determined by microplate BCA method | 
                                
                                    | Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |