Recombinant Human CACNG2, His-tagged

• Cat.No.: CACNG2-10642H
• Product Overview: Recombinant Human CACNG2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: C-term-148a.a.
• Description: The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. This gene is a susceptibility locus for schizophrenia.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CACNG2 calcium channel, voltage-dependent, gamma subunit 2 [ Homo sapiens ]
• Official Symbol: CACNG2
• Synonyms: CACNG2; calcium channel, voltage-dependent, gamma subunit 2; voltage-dependent calcium channel gamma-2 subunit; MGC138502; MGC138504; stargazin; TARP gamma-2; transmembrane AMPAR regulatory protein gamma-2; neuronal voltage-gated calcium channel gamma-2 subunit; MRD10; FLJ41437
• Gene ID: 10369
• mRNA Refseq: NM_006078
• Protein Refseq: NP_006069
• MIM: 602911
• UniProt ID: Q9Y698
• Chromosome Location: 22q13.1
• Pathway: Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels, organism-specific biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem
• Function: protein binding; voltage-gated calcium channel activity; voltage-gated ion channel activity