Recombinant Human CAPG

• Cat.No.: CAPG-26482TH
• Product Overview: Recombinant full length Human Actin Regulatory Protein CAPG; amino acids 1-348, MWt 38.5kDa.

Specification

• Description: This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed, but have not been fully described.
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MYTAIPQSGS PFPGSVQDPG LHVWRVEKLK PVPVAQENQG VFFSGDSYLV LHNGPEEVSH LHLWIGQQSS RDEQGACAVL AVHLNTLLGE RPVQHREVQG NESDLFMSYF PRGLKYQEGG VESAFHKTST GAPAAIKKLY QVKGKKNIRA TERALNWDSF NTGDCFILDL GQNIFAWCGG KSNILERNKA RDLALAIRDS ERQGKAQVEI VTDGEEPAEM IQVLGPKPAL KEGNPEEDLT ADKANAQAAA LYKVSDATGQ MNLTKVADSS PFALELLISD DCFVLDNGLC GKIYIWKGRK ANEKERQAAL QVAEGFISRM QYAPNTQVEI LPQGRESPIF KQFFKDWK

Gene Information

• Gene Name: CAPG capping protein (actin filament), gelsolin-like [ Homo sapiens ]
• Official Symbol: CAPG
• Synonyms: CAPG; capping protein (actin filament), gelsolin-like; AFCP; macrophage-capping protein; macrophage capping protein; MCP
• Gene ID: 822
• mRNA Refseq: NM_001747
• Protein Refseq: NP_001738
• MIM: 153615
• Uniprot ID: P40121
• Chromosome Location: 2p11.2
• Function: actin binding