Recombinant Human CAPG Protein, GST-Tagged

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Recombinant Human CAPG Protein, GST-Tagged

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Cat.No. : CAPG-0353H
Product Overview : Human CAPG full-length ORF (AAH00728.1, 1 a.a. - 348 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 63.8 kDa
AA Sequence : MYTAIPQSGS PFPGSVQDPG LHVWRVEKLK PVPVAQENQG VFFSGDSYLV LHNGPEEVSH LHLWIGQQSS RDEQGACAVL AVHLNTLLGE RPVQHREVQG NESDLFMSYF PRGLKYQEGG VESAFHKTST GAPAAIKKLY QVKGKKNIRA TERALNWDSF NTGDCFILDL GQNIFAWCGG KSNILERNKA RDLALAIRDS ERQGKAQVEI VTDGEEPAEM IQVLGPKPAL KEGNPEEDLT ADKANAQAAA LYKVSDATGQ MNLTKVADSS PFALELLISD DCFVLDNGLC GKIYIWKGRK ANEKERQAAL QVAEGFISRM QYAPNTQVEI LPQGRESPIF KQFFKDWK
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CAPG capping protein (actin filament), gelsolin-like [ Homo sapiens ]
Official Symbol : CAPG
Synonyms : CAPG; capping protein (actin filament), gelsolin-like; AFCP; macrophage-capping protein; macrophage capping protein; MCP; gelsolin-like capping protein; actin regulatory protein CAP-G; actin-regulatory protein CAP-G;
Gene ID : 822
mRNA Refseq : NM_001256139
Protein Refseq : NP_001243068
MIM : 153615
UniProt ID : P40121

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