Recombinant Human CAPG Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CAPG-3108H
• Product Overview: CAPG MS Standard C13 and N15-labeled recombinant protein (NP_001738) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 38.5 kDa
• AA Sequence: MYTAIPQSGSPFPGSVQDPGLHVWR VEKLKPVPVAQENQGVFFSGDSYLV LHNGPEEVSHLHLWIGQQSSRDEQG ACAVLAVHLNTLLGERPVQHREVQG NESDLFMSYFPRGLKYQEGGVESAF HKTSTGAPAAIKKLYQVKGKKNIRA TERALNWDSFNTGDCFILDLGQNIF AWCGGKSNILERNKARDLALAIRDS ERQGKAQVEIVTDGEEPAEMIQVLG PKPALKEGNPEEDLTADKANAQAAA LYKVSDATGQMNLTKVADSSPFALE LLISDDCFVLDNGLCGKIYIWKGRK ANEKERQAALQVAEGFISRMQYAPN TQVEILPQGRESPIFKQFFKDWKTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CAPG capping actin protein, gelsolin like [ Homo sapiens (human) ]
• Official Symbol: CAPG
• Synonyms: CAPG; capping protein (actin filament), gelsolin-like; AFCP; macrophage-capping protein; macrophage capping protein; MCP; gelsolin-like capping protein; actin regulatory protein CAP-G; actin-regulatory protein CAP-G
• Gene ID: 822
• mRNA Refseq: NM_001747
• Protein Refseq: NP_001738
• MIM: 153615
• UniProt ID: P40121