Recombinant Human CAST Protein (1-667 aa), His-tagged

• Cat.No.: CAST-1350H
• Product Overview: Recombinant Human CAST Protein (1-667 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Neuroscience. Protein Description: Full Length of isoform 4.

Specification

• Description: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmort tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.
• Source: Yeast
• Species: Human
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 73.9 kDa
• Protein length: 1-667 aa
• AA Sequence: MNPTETKAVKTEPEKKSQSTKPKSL PKQASDTGSNDAHNKKAVSRSAEQQ PSEKSTEPKTKPQDMISAGGESVAG ITAISGKPGDKKKEKKSLTPAVPVE SKPDKPSGKSGMDAALDDLIDTLGG PEETEEENTTYTGPEVSDPMSSTYI EELGKREVTIPPKYRELLAKKEGIT GPPADSSKPIGPDDAIDALSSDFTC GSPTAAGKKTEKEESTEVLKAQSAG TVRSAAPPQEKKRKVEKDTMSDQAL EALSASLGTRQAEPELDLRSIKEVD EAKAKEEKLEKCGEDDETIPSEYRL KPATDKDGKPLLPEPEEKPKPRSES ELIDELSEDFDRSECKEKPSKPTEK TEESKAAAPAPVSEAVCRTSMCSIQ SAPPEPATLKGTVPDDAVEALADSL GKKEADPEDGKPVMDKVKEKAKEED REKLGEKEETIPPDYRLEEVKDKDG KPLLPKESKEQLPPMSEDFLLDALS EDFSGPQNASSLKFEDAKLAAAISE VVSQTPASTTQAGAPPRDTSQSDKD LDDALDKLSDSLGQRQPDPDENKPM EDKVKEKAKAEHRDKLGERDDTIPP EYRHLLDDNGQDKPVKPPTKKSEDS KKPADDQDPIDALSGDLDSCPSTTE TSQNTAKDKCKKAASSSKAPKNGGK AKDSAKTTEETSKPKDD
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: CAST calpastatin [ Homo sapiens ]
• Official Symbol: CAST
• Synonyms: CAST; calpastatin; BS-17; MGC9402
• Gene ID: 831
• mRNA Refseq: NM_001042440
• Protein Refseq: NP_001035905
• MIM: 114090
• UniProt ID: P20810