| Cat.No. : |
CBFA2T3-0453H |
| Product Overview : |
Human CBFA2T3 full-length ORF (AAH62624.1, 1 a.a. - 615 a.a.) recombinant protein with GST-tag at N-terminal. |
| Description : |
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010] |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Molecular Mass : |
93.3 kDa |
| AA Sequence : |
MPASRLRDRA ASSASGSTCG SMSQTHPVLE SGLLASAGCS APRGPRKGGP APVDRKAKAS AMPDSPAEVK TQPRSTPPSM PPPPPAASQG ATRPPSFTPH TLMNGSSHSP TAINGAPCTP NGFSNGPATS STASLSTQHL PPACGARQLS KLKRFLTTLQ QFGSDISPEI GERVRTLVLG LVNSTLTIEE FHSKLQEATN FPLRPFVIPF LKANLPLLQR ELLHCARLAK QTPAQYLAQH EQLLLDASAS SPIDSSELLL EVNENGKRRT PDRTKENGSD RDPLHPQRYS PSNGPPQPTP PPHYRLEDIA MAHHFRDAYR HPDPRELRER HRPLVVPGSR QEEVIDHKLT EREWAEEWKH LNNLLNCIMD MVEKTRRSLT VLRRCQEADR EELNHWARRY SDAEDTKKGP APAAARPRSS SAGPEGPQLD VPREFLPRTL TGYVPEDIWR KAEEAVNEVK RQAMSELQKA VSDAERKAHE LITTERAKME RALAEAKRQA SEDALTVINQ QEDSSESCWN CGRKASETCS GCNAARYCGS FCQHRDWEKH HHVCGQSLQG PTAVVADPVP GPPEAAHSLG PSLPVGAASP SEAGSAGPSR PGSPSPPGPL DTVPR |
| Applications : |
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Quality Control Testing : |
12.5% SDS-PAGE Stained with Coomassie Blue.
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