Recombinant Human CBFA2T3 Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | CBFA2T3-2858H |
| Product Overview : | CBFA2T3 MS Standard C13 and N15-labeled recombinant protein (NP_005178) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 71.2 kDa |
| AA Sequence : | MPASRLRDRA ASSASGSTCG SMSQTHPVLE SGLLASAGCS APRGPRKGGP APVDRKAKAS AMPDSPAEVK TQPRSTPPSM PPPPPAASQG ATRPPSFTPH THREDGPATL PHGRFHGCLK WSMVCLLMNG SSHSPTAING APCTPNGFSN GPATSSTASL STQHLPPACG ARQLSKLKRF LTTLQQFGSD ISPEIGERVR TLVLGLVNST LTIEEFHSKL QEATNFPLRP LVIPFLKANL PLLQRELLHC ARLAKQTPAQ YLAQHEQLLL DASASSPIDS SELLLEVNEN GKRRTPDRTK ENGSDRDPLH PEHLSKRPCT LNPAQRYSPS NGPPQPTPPP HYRLEDIAMA HHFRDAYRHP DPRELRERHR PLVVPGSRQE EVIDHKLTER EWAEEWKHLN NLLNCIMDMV EKTRRSLTVL RRCQEADREE LNHWARRYSD AEDTKKGPAP AAARPRSSSA GPEGPQLDVP REFLPRTLTG YVPEDIWRKA EEAVNEVKRQ AMSELQKAVS DAERKAHELI TTERAKMERA LAEAKRQASE DALTVINQQE DSSESCWNCG RKASETCSGC NAARYCGSFC QHRDWEKHHH VCGQSLQGPT AVVADPVPGP PEAAHSLGPS LPVGAASPSE AGSAGPSRPG SPSPPGPLDT VPRTRTRPLE QKLISEEDLA ANDILDYKDD DDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | CBFA2T3 CBFA2/RUNX1 partner transcriptional co-repressor 3 [ Homo sapiens (human) ] |
| Official Symbol : | CBFA2T3 |
| Synonyms : | CBFA2T3; core-binding factor, runt domain, alpha subunit 2; translocated to, 3; protein CBFA2T3; MTG16; MTGR2; myeloid translocation gene 8 and 16b; ZMYND4; MTG8-related gene 2; MTG8-related protein 2; zinc finger MYND domain-containing protein 4; myeloid translocation gene on chromosome 16 protein; ETO2; |
| Gene ID : | 863 |
| mRNA Refseq : | NM_005187 |
| Protein Refseq : | NP_005178 |
| MIM : | 603870 |
| UniProt ID : | O75081 |
◆ Recombinant Protein
| CBFA2T3-0453H | Recombinant Human CBFA2T3 Protein, GST-Tagged | +Inquiry |
| Cbfa2t3-786M | Recombinant Mouse Cbfa2t3 Protein, MYC/DDK-tagged | +Inquiry |
| CBFA2T3-2730H | Recombinant Human CBFA2T3 Protein, MYC/DDK-tagged | +Inquiry |
| CBFA2T3-2293C | Recombinant Chicken CBFA2T3 | +Inquiry |
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◆ Lysates
| CBFA2T3-286HCL | Recombinant Human CBFA2T3 cell lysate | +Inquiry |
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