| Description : |
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
71.2 kDa |
| AA Sequence : |
MPASRLRDRAASSASGSTCGSMSQT HPVLESGLLASAGCSAPRGPRKGGP APVDRKAKASAMPDSPAEVKTQPRS TPPSMPPPPPAASQGATRPPSFTPH THREDGPATLPHGRFHGCLKWSMVC LLMNGSSHSPTAINGAPCTPNGFSN GPATSSTASLSTQHLPPACGARQLS KLKRFLTTLQQFGSDISPEIGERVR TLVLGLVNSTLTIEEFHSKLQEATN FPLRPLVIPFLKANLPLLQRELLHC ARLAKQTPAQYLAQHEQLLLDASAS SPIDSSELLLEVNENGKRRTPDRTK ENGSDRDPLHPEHLSKRPCTLNPAQ RYSPSNGPPQPTPPPHYRLEDIAMA HHFRDAYRHPDPRELRERHRPLVVP GSRQEEVIDHKLTEREWAEEWKHLN NLLNCIMDMVEKTRRSLTVLRRCQE ADREELNHWARRYSDAEDTKKGPAP AAARPRSSSAGPEGPQLDVPREFLP RTLTGYVPEDIWRKAEEAVNEVKRQ AMSELQKAVSDAERKAHELITTERA KMERALAEAKRQASEDALTVINQQE DSSESCWNCGRKASETCSGCNAARY CGSFCQHRDWEKHHHVCGQSLQGPT AVVADPVPGPPEAAHSLGPSLPVGA ASPSEAGSAGPSRPGSPSPPGPLDT VPRTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
