- Human(4)
- Mouse(1)
- Rat(1)
- Rhesus Macaque(1)
Recombinant Human CBX7 Protein (1-251 aa), His-tagged
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| Cat.No. : | CBX7-1353H |
| Product Overview : | Recombinant Human CBX7 Protein (1-251 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Transcription. Protein Description: Full Length. |
| Description : | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin rodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity. |
| Source : | Yeast |
| Species : | Human |
| Tag : | His |
| Form : | Tris-based buffer,50% glycerol |
| Molecular Mass : | 30.3 kDa |
| Protein length : | 1-251 aa |
| AA Sequence : | MELSAIGEQVFAVES IRKKRVRKGKVEYLV KWKGWPPKYSTWEPE EHILDPRLVMAYEEK EERDRASGYRKRGPK PKRLLLQRLYSMDLR SSHKAKGKEKLCFSL TCPLGSGSPEGVVKA GAPELVDKGPLVPTL PFPLRKPRKAHKYLR LSRKKFPPRGPNLES HSHRRELFLQEPPAP DVLQAAGEWEPAAQP PEEEADADLAEGPPP WTPALPSSEVTVTDI TANSITVTFREAQAA EGFFRDRSGKF |
| Purity : | > 90% as determined by SDS-PAGE. |
| Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. |
| Figure : |
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel. |
| Gene Name : | CBX7 chromobox homolog 7 [ Homo sapiens ] |
| Official Symbol : | CBX7 |
| Synonyms : | CBX7; chromobox homolog 7; |
| Gene ID : | 23492 |
| mRNA Refseq : | NM_175709 |
| Protein Refseq : | NP_783640 |
| MIM : | 608457 |
| UniProt ID : | O95931 |
◆ Recombinant Protein
| CBX7-0485H | Recombinant Human CBX7 Protein, GST-Tagged | +Inquiry |
| CBX7-2797M | Recombinant Mouse CBX7 Protein | +Inquiry |
| CBX7-10772H | Recombinant Human CBX7, His-tagged | +Inquiry |
| CBX7-649R | Recombinant Rhesus monkey CBX7 Protein, His-tagged | +Inquiry |
| CBX7-1163R | Recombinant Rat CBX7 Protein | +Inquiry |
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◆ Lysates
| CBX7-7801HCL | Recombinant Human CBX7 293 Cell Lysate | +Inquiry |
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