Recombinant Human CBX7 Protein (1-251 aa), His-tagged CBX7-1353H

Recombinant Human CBX7 Protein (1-251 aa), His-tagged

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Recombinant Human CBX7 Protein (1-251 aa), His-tagged

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Cat.No. : CBX7-1353H
Product Overview : Recombinant Human CBX7 Protein (1-251 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Transcription. Protein Description: Full Length.
Description : Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin rodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
Source : Yeast
Species : Human
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 30.3 kDa
Protein length : 1-251 aa
AA Sequence : MELSAIGEQVFAVES IRKKRVRKGKVEYLV KWKGWPPKYSTWEPE EHILDPRLVMAYEEK EERDRASGYRKRGPK PKRLLLQRLYSMDLR SSHKAKGKEKLCFSL TCPLGSGSPEGVVKA GAPELVDKGPLVPTL PFPLRKPRKAHKYLR LSRKKFPPRGPNLES HSHRRELFLQEPPAP DVLQAAGEWEPAAQP PEEEADADLAEGPPP WTPALPSSEVTVTDI TANSITVTFREAQAA EGFFRDRSGKF
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : CBX7 chromobox homolog 7 [ Homo sapiens ]
Official Symbol : CBX7
Synonyms : CBX7; chromobox homolog 7;
Gene ID : 23492
mRNA Refseq : NM_175709
Protein Refseq : NP_783640
MIM : 608457
UniProt ID : O95931

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