Recombinant Human CC2D1A Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CC2D1A-1522H
• Product Overview: CC2D1A MS Standard C13 and N15-labeled recombinant protein (NP_060191) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in a nonsyndromic form of cognitive disability (MRT3).
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 104.1 kDa
• AA Sequence: MHKRKGPPGPPGRGAAAARQLGLLV DLSPDGLMIPEDGANDEELEAEFLA LVGGQPPALEKLKGKGPLPMEAIEK MASLCMRDPDEDEEEGTDEDDLEAD DDLLAELNEVLGEEQKASETPPPVA QPKPEAPHPGLETTLQERLALYQTA IESARQAGDSAKMRRYDRGLKTLEN LLASIRKGNAIDEADIPPPVAIGKG PASTPTYSPAPTQPAPRIASAPEPR VTLEGPSATAPASSPGLAKPQMPPG PCSPGPLAQLQSRQRDYKLAALHAK QQGDTTAAARHFRVAKSFDAVLEAL SRGEPVDLSCLPPPPDQLPPDPPSP PSQPPTPATAPSTTEVPPPPRTLLE ALEQRMERYQVAAAQAKSKGDQRKA RMHERIVKQYQDAIRAHKAGRAVDV AELPVPPGFPPIQGLEATKPTQQSL VGVLETAMKLANQDEGPEDEEDEVP KKQNSPVAPTAQPKAPPSRTPQSGS APTAKAPPKATSTRAQQQLAFLEGR KKQLLQAALRAKQKNDVEGAKMHLR QAKGLEPMLEASRNGLPVDITKVPP APVNKDDFALVQRPGPGLSQEAARR YGELTKLIRQQHEMCLNHSNQFTQL GNITETTKFEKLAEDCKRSMDILKQ AFVRGLPTPTARFEQRTFSVIKIFP DLSSNDMLLFIVKGINLPTPPGLSP GDLDVFVRFDFPYPNVEEAQKDKTS VIKNTDSPEFKEQFKLCINRSHRGF RRAIQTKGIKFEVVHKGGLFKTDRV LGTAQLKLDALEIACEVREILEVLD GRRPTGGRLEVMVRIREPLTAQQLE TTTERWLVIDPVPAAVPTQVAGPKG KAPPVPAPARESGNRSARPLHSLSV LAFDQERLERKILALRQARRPVPPE VAQQYQDIMQRSQWQRAQLEQGGVG IRREYAAQLERQLQFYTEAARRLGN DGSRDAAKEALYRRNLVESELQRLR RTRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CC2D1A coiled-coil and C2 domain containing 1A [ Homo sapiens (human) ]
• Official Symbol: CC2D1A
• Synonyms: CC2D1A; coiled-coil and C2 domain containing 1A; coiled-coil and C2 domain-containing protein 1A; FLJ20241; mental retardation; nonsyndromic; autosomal recessive; 3; MRT3; Akt kinase-interacting protein 1; putative NFkB activating protein; FRE under dual repression-binding protein 1; putative NF-kappa-B-activating protein 023N; mental retardation, nonsyndromic, autosomal recessive, 3; five repressor element under dual repression-binding protein 1; five prime repressor element under dual repression-binding protein 1; FREUD-1; Freud-1/Aki1; FLJ41160
• Gene ID: 54862
• mRNA Refseq: NM_017721
• Protein Refseq: NP_060191
• MIM: 610055
• UniProt ID: Q6P1N0