Recombinant Human CC2D1A Protein, His-tagged

• Cat.No.: CC2D1A-636H
• Product Overview: Recombinant Human CC2D1A Protein (Pro675-Ser944) with His tag was expressed in E. coli.

Specification

• Description: This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in a nonsyndromic form of cognitive disability (MRT3).
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 34.3 kDa; Accurate Molecular Mass: 34 kDa
• Protein length: Pro675-Ser944
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: CC2D1A coiled-coil and C2 domain containing 1A [ Homo sapiens (human) ]
• Official Symbol: CC2D1A
• Synonyms: CC2D1A; coiled-coil and C2 domain containing 1A; coiled-coil and C2 domain-containing protein 1A; FLJ20241; mental retardation; nonsyndromic; autosomal recessive; 3; MRT3; Akt kinase-interacting protein 1; putative NFkB activating protein; FRE under dual repression-binding protein 1; putative NF-kappa-B-activating protein 023N; mental retardation, nonsyndromic, autosomal recessive, 3; five repressor element under dual repression-binding protein 1; five prime repressor element under dual repression-binding protein 1; FREUD-1; Freud-1/Aki1; FLJ41160
• Gene ID: 54862
• mRNA Refseq: NM_017721
• Protein Refseq: NP_060191
• MIM: 610055
• UniProt ID: Q6P1N0