Recombinant Human CCL11 protein, His & GST-tagged

• Cat.No.: CCL11-595H
• Product Overview: Recombinant Human CCL11 (P51671) aa. (Gly24~Pro97) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 40.8kDa
• Protein length: Gly24~Pro97 (Accession # Q6I9T4)
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Characteristic: The isoelectric point is 8.8.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4

Gene Information

• Gene Name: CCL11 C-C motif chemokine ligand 11 [ Homo sapiens (human) ]
• Official Symbol: CCL11
• Synonyms: CCL11; C-C motif chemokine ligand 11; SCYA11; eotaxin; chemokine (C-C motif) ligand 11; eosinophil chemotactic protein; eotaxin-1; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
• Gene ID: 6356
• mRNA Refseq: NM_002986.2
• Protein Refseq: NP_002977.1
• UniProt ID: P51671