Recombinant Human CCL11 protein, His & GST-tagged

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Recombinant Human CCL11 protein, His & GST-tagged

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Cat.No. : CCL11-595H
Product Overview : Recombinant Human CCL11 (P51671) aa. (Gly24~Pro97) fused with N-terminal His & GST tag was produced in E. coli cells.
Description : This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
Source : E. coli
Species : Human
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 40.8kDa
Protein length : Gly24~Pro97 (Accession # Q6I9T4)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Characteristic : The isoelectric point is 8.8.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4
SDS-PAGE :

Gene Name : CCL11 C-C motif chemokine ligand 11 [ Homo sapiens (human) ]
Official Symbol : CCL11
Synonyms : CCL11; C-C motif chemokine ligand 11; SCYA11; eotaxin; chemokine (C-C motif) ligand 11; eosinophil chemotactic protein; eotaxin-1; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
Gene ID : 6356
mRNA Refseq : NM_002986.2
Protein Refseq : NP_002977.1
UniProt ID : P51671
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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