- Human(21)
Recombinant Human CCL14, His-tagged
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Cat.No. : | CCL14-167H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant human CCL14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. |
Description : | CCL14, also known as Chemokine (C-C motif) ligand 14, is member of a superfamily of inducible, secreted, proinflammatory cytokines. It has weak activities on human monocytes and acts via receptors that also recognize MIP-1α. It also enhances the proliferation of CD34 myeloid progenitor cells. The processed form of CCL14, designated HCC-1(9-74), is a chemotactic factor that attracts monocytes, eosinophils and T cells and is a ligand for CCR1, CCR3 and CCR5. |
Source : | E.coli. |
Form : | Liquid. In Phosphate Buffered Saline pH7.4 containing 10% glycerol. |
Molecular Weight : | 10.9 kDa (95aa) confirmed by MALDI-TOF. |
Purity : | > 95% by SDS - PAGE. |
Concentration : | 0.5 mg/ml (determined by Bradford assay). |
Endotoxin Level : | < 1.0 EU per 1 μg of protein (determined by LAL method). |
Sequences Of Amino Acids : | MGSSHHHHHH SSGLVPRGSH MTKTESSSRG PYHPSECCFT YTTYKIPRQR IMDYYETNSQ CSKPGIVFIT KRGHSVCTNP SDKWVQDYIK DMKEN. |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Pathways : | Cytokine-cytokine receptor interaction |
Gene Name : | CCL14 chemokine (C-C motif) ligand 14 [ Homo sapiens ] |
Synonyms : | OTTHUMP00000176860; SCYA14; SY14; SCYL2; NCC-2; NCC2; CKb1; MCIF; CC-1; CC-3; CCL14; HCC-1; HCC-1(1-74); HCC-1/HCC-3; chemokine (C-C motif) ligand 14; chemokine CC-1; HCC-3; chemokine CC-3; Chemokine CC-1/CC-3; FLJ16015; Small-inducible cytokine A14; small inducible cytokine subfamily A (Cys-Cys), member 14 |
Gene ID : | 6358 |
mRNA Refseq : | NM_032963 |
Protein Refseq : | NP_116739 |
MIM : | 601392 |
UniProt ID : | Q16627 |
Chromosome Location : | 17q11.2 |
Function : | chemokine activity; protein binding; signal transducer activity |
◆ Recombinant Protein
CCL14-384C | Recombinant Human CCL14 Protein (72 aa) | +Inquiry |
CCL14-0609H | Recombinant Human CCL14 Protein, GST-Tagged | +Inquiry |
CCL14-011H | Recombinant Human CCL14 Protein | +Inquiry |
CCL14-012H | Recombinant Human CCL14 Protein, Biotinylated | +Inquiry |
CCL14-81H | Recombinant Human CCL14 Protein, Biotin-tagged | +Inquiry |
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◆ Lysates
CCL14-7732HCL | Recombinant Human CCL14 293 Cell Lysate | +Inquiry |
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CCL1CCL11Ccl12CCL13CCL14CCL15CCL16CCL17CCL18CCL19CCL2CCL20CCL21Ccl21cCCL22CCL23CCL24CCL25CCL26CCL27Ccl27aCCL28CCL3CCL3L1Ccl4CCL5Ccl6CCL7CCL8Ccl9CCL4L2Ccl21aCCL4L1CCL3L3Ccl21bCcl27b
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