Recombinant Human CCL14 protein
| Cat.No. : | CCL14-0608H |
| Product Overview : | Recombinant Human CCL14 protein (72 a.a.) was expressed in Escherichia coli. |
- Specification
- Gene Information
- Related Products
| Description : | Human CCL14 is belonging to the CC chemokine family. It has two isoforms, CCL14a (HCC-1) and CCL14b (HCC-3). The sequence of HCC-3 differs from HCC-1 as follow: 27-27 R→ QTGGKPKVVKIQLKLVG. CCL14 was first isolated from the hemofiltrate of human patients with chronic renal failure. CCL14 promotes chemotaxis of T lymphocytes, monocytes and eosinophils, and inhibits infection of M-tropic human immunodeficiency virus type 1 and is a ligand for CCR1, CCR3 and CCR5. CCL14 is expressed constitutively in several normal tissues: spleen, liver, skeletal and heart muscle, gut, and bone marrow, present at high concentrations in plasma. |
| Source : | E.coli |
| Species : | Human |
| Form : | Lyophilized from a 0.2μm filtered concentrated solution in 20 mM PB, pH 7.4, 100 mM NaCl. |
| Bio-activity : | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration of 5.0-20 ng/ml. |
| Molecular Mass : | Approximately 8.4 kDa, a single non-glycosylated polypeptide chain containing 72 amino acids. |
| Protein length : | 72 |
| AA Sequence : | TESSSRGPYHPSECCFTYTTYKIPR QRIMDYYETNSQCSKPGIVFITKRG HSVCTNPSDKWVQDYIKDMKEN |
| Endotoxin : | Less than 1 EU/μg of rHuHCC-1/CCL14 as determined by LAL method. |
| Purity : | >96% by SDS-PAGE and HPLC analysis. |
| Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
| Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions. |
| Gene Name : | CCL14 |
| Official Symbol : | CCL14 |
| Synonyms : | CCL14; chemokine (C-C motif) ligand 14; SCYA14, small inducible cytokine subfamily A (Cys Cys), member 14; C-C motif chemokine 14; CKb1; HCC 1; HCC 3; MCIF; NCC 2; SCYL2; chemokine CC-3; new CC chemokine 2; chemokine CC-1/CC-3; hemofiltrate CC chemokine 1; small-inducible cytokine A14; small inducible cytokine subfamily A (Cys-Cys), member 14; CC-1; CC-3; CKB1; NCC2; SY14; HCC-1; HCC-3; NCC-2; SCYA14; HCC-1(1-74); HCC-1/HCC-3; FLJ16015; |
| Gene ID : | 6358 |
| mRNA Refseq : | NM_032962 |
| Protein Refseq : | NP_116738 |
| MIM : | 601392 |
| UniProt ID : | Q16627 |
Products Types
| ◆ Recombinant Protein | ||
| CCL14-012H | Recombinant Human CCL14 Protein, Biotinylated | +Inquiry |
| CCL14-011H | Recombinant Human CCL14 Protein | +Inquiry |
| CCL14-0609H | Recombinant Human CCL14 Protein, GST-Tagged | +Inquiry |
| CCL14-384C | Active Recombinant Human CCL14 Protein (72 aa) | +Inquiry |
| CCL14-1309H | Recombinant Human CCL14 Protein (Thr20-Asn93), C-His tagged | +Inquiry |
| ◆ Lysates | ||
| CCL14-7732HCL | Recombinant Human CCL14 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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