- Human(14)
- Mouse(6)
- Rat(2)
- Rhesus Macaque(1)
Recombinant Human CCL28 Protein
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Cat.No. : | CCL28-54H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Human CCL28 Protein was expressed in E. coli. |
Description : | Human CCL28 is chemokine that is constitutively expressed by epithelial cells in diverse mucosal tissues and is known to attract a variety of immune cell types including T-cell subsets and eosinophils through activation of the G protein-coupled receptors CCR10 and CCR3. CCL28 contains an extended C-terminal domain consisting of ~40 flexible amino acids. In addition to the two disulfide bonds that are conserved throughout the chemokine family, two additional cysteine residues at positions 30 and 80 form a novel disulfide linkage between the folded chemokine domain and the flexible C-terminus. Human CCL28 is expressed as an immature polypeptide 127 amino acids in length. Two different mature N-terminal sequences have been described due to uncertainty in the site of cleavage by signal peptidase. CCL28(4-108) is described in the NCIB GenPept entry as the mature form based on an ab initio prediction of the site of signal peptide cleavage. It consists of residues 23-127 of the expressed protein and may exhibit higher potency as a CCR10 agonist than the longer version [CCL28(1-108)] that includes three additional N-terminal residues. |
Source : | E. coli |
Species : | Human |
Form : | Lyophilized |
Molecular Mass : | 12.070 kDa |
Protein length : | 114 amino acid |
AA Sequence : | ILPIASSCCT EVSHHISRRL LERVNMCRIQ RADGDCDLAA VILHVKRRRI CVSPHNHTVK QWMKV QAAKKNGKGN VCHRKKHHGK RNSNRAHQGK HETYGHKTPY |
Endotoxin : | Endotoxin-free <0.01 EU/ug |
Purity : | Purity assessed by HPLC, Mass Spectrometry, and NMR |
Storage : | Store at -20 to -80 centigrade for 12 months; Store at 4 centigrade for 6 months; Store at RT for 1 month. |
tmpcolum67 : | C-C motif chemokine ligand 28 |
Figure : |
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Gene Name : | CCL28 C-C motif chemokine ligand 28 [ Homo sapiens (human) ] |
Official Symbol : | CCL28 |
Synonyms : | MEC; CCK1; SCYA28 |
Gene ID : | 56477 |
mRNA Refseq : | NM_148672 |
Protein Refseq : | NP_683513 |
MIM : | 605240 |
UniProt ID : | Q9NRJ3 |
◆ Recombinant Protein
Ccl28-2036M | Recombinant Mouse Ccl28 Protein | +Inquiry |
CCL28-0634H | Recombinant Human CCL28 Protein, GST-Tagged | +Inquiry |
Ccl28-152M | Recombinant Mouse Ccl28 Protein | +Inquiry |
Ccl28-639R | Recombinant Rat Ccl28 protein | +Inquiry |
CCL28-151H | Recombinant Human CCL28 Protein, DYKDDDDK-tagged | +Inquiry |
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◆ Lysates
CCL28-7724HCL | Recombinant Human CCL28 293 Cell Lysate | +Inquiry |
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CCL1CCL11Ccl12CCL13CCL14CCL15CCL16CCL17CCL18CCL19CCL2CCL20CCL21Ccl21cCCL22CCL23CCL24CCL25CCL26CCL27Ccl27aCCL28CCL3CCL3L1Ccl4CCL5Ccl6CCL7CCL8Ccl9CCL4L2Ccl21aCCL4L1CCL3L3Ccl21bCcl27b
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