Recombinant Human CCL3L3

Cat.No. : CCL3L3-29222TH
Product Overview : Recombinantprotein, corresponding to amino acids 24-93 of Human LD78 beta precursor molecule. (A 7.7 kDa protein; including the four conserved cysteine residues present in CC chemokines).
  • Specification
  • Gene Information
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Description : This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. This protein binds to several chemokine receptors including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals; most individuals have 1-6 copies in the diploid genome, although rare individuals have zero or more than six copies. The human genome reference assembly contains two full copies of the gene (CCL3L3 and CCL3L1) and a partial pseudogene. This record represents the more centromeric full-length gene.
Source : E. coli
Form : Lyophilised:Reconsitute to 1mg/ml in distilled water.
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneEndotoxin level is less than 0.1 ng per μg (1EU/μg).
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequences of amino acids : APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA
Sequence Similarities : Belongs to the intercrine beta (chemokine CC) family.
Gene Name : CCL3L3 chemokine (C-C motif) ligand 3-like 3 [ Homo sapiens ]
Official Symbol : CCL3L3
Synonyms : CCL3L3; chemokine (C-C motif) ligand 3-like 3; C-C motif chemokine 3-like 1; MGC12815;
Gene ID : 414062
mRNA Refseq : NM_001001437
Protein Refseq : NP_001001437
MIM : 609468
Uniprot ID : P16619
Chromosome Location : 17q21.1
Pathway : Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem;
Function : chemokine activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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