Recombinant Human CCR3 Protein
Cat.No. : | CCR3-0690H |
Product Overview : | Human CCR3 full-length ORF (NP_001828.1) recombinant protein without tag. |
- Specification
- Gene Information
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Description : | The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009] |
Source : | Wheat Germ |
Species : | Human |
Form : | Liquid |
Molecular Mass : | 41 kDa |
AA Sequence : | MTTSLDTVETFGTTSYYDDVGLLCE KADTRALMAQFVPPLYSLVFTVGLL GNVVVVMILIKYRRLRIMTNIYLLN LAISDLLFLVTLPFWIHYVRGHNWV FGHGMCKLLSGFYHTGLYSEIFFII LLTIDRYLAIVHAVFALRARTVTFG VITSIVTWGLAVLAALPEFIFYETE ELFEETLCSALYPEDTVYSWRHFHT LRMTIFCLVLPLLVMAICYTGIIKT LLRCPSKKKYKAIRLIFVIMAVFFI FWTPYNVAILLSSYQSILFGNDCER SKHLDLVMLVTEVIAYSHCCMNPVI YAFVGERFRKYLRHFFHRHLLMHLG RYIPFLPSEKLERTSSVSPSTAEPE LSIVF |
Applications : | Antibody Production Functional Study Compound Screening |
Usage : | Heating may cause protein aggregation. Please do not heat this product before electrophoresis. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
Gene Name : | CCR3 chemokine (C-C motif) receptor 3 [ Homo sapiens ] |
Official Symbol : | CCR3 |
Synonyms : | CCR3; chemokine (C-C motif) receptor 3; CMKBR3; C-C chemokine receptor type 3; CC CKR 3; CD193; CKR3; CCR-3; C-C CKR-3; b-chemokine receptor; CC chemokine receptor 3; eosinophil eotaxin receptor; eosinophil CC chemokine receptor 3; CC-CKR-3; MGC102841; |
Gene ID : | 1232 |
mRNA Refseq : | NM_001164680 |
Protein Refseq : | NP_001158152 |
MIM : | 601268 |
UniProt ID : | P51677 |
Products Types
◆ Recombinant Protein | ||
CCR3-0691H | Recombinant Human CCR3 Protein, GST-Tagged | +Inquiry |
CCR3-886R | Recombinant Rat CCR3 Protein, His (Fc)-Avi-tagged | +Inquiry |
CCR3-533R | Recombinant Rhesus Macaque CCR3 Protein, His (Fc)-Avi-tagged | +Inquiry |
CCR3-1422M | Recombinant Mouse CCR3 Protein, His (Fc)-Avi-tagged | +Inquiry |
CCR3-126C | Recombinant Cynomolgus Monkey CCR3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CCR3-7694HCL | Recombinant Human CCR3 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1639 | CCR3 CHO-K1 β-Arrestin GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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