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Recombinant Human CCR7 Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | CCR7-4640H |
| Product Overview : | CCR7 MS Standard C13 and N15-labeled recombinant protein (NP_001829) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 42.9 kDa |
| AA Sequence : | MDLGKPMKSV LVVALLVIFQ VCLCQDEVTD DYIGDNTTVD YTLFESLCSK KDVRNFKAWF LPIMYSIICF VGLLGNGLVV LTYIYFKRLK TMTDTYLLNL AVADILFLLT LPFWAYSAAK SWVFGVHFCK LIFAIYKMSF FSGMLLLLCI SIDRYVAIVQ AVSAHRHRAR VLLISKLSCV GIWILATVLS IPELLYSDLQ RSSSEQAMRC SLITEHVEAF ITIQVAQMVI GFLVPLLAMS FCYLVIIRTL LQARNFERNK AIKVIIAVVV VFIVFQLPYN GVVLAQTVAN FNITSSTCEL SKQLNIAYDV TYSLACVRCC VNPFLYAFIG VKFRNDLFKL FKDLGCLSQE QLRQWSSCRH IRRSSMSVEA ETTTTFSPTR TRPLEQKLIS EEDLAANDIL DYKDDDDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | CCR7 C-C motif chemokine receptor 7 [ Homo sapiens (human) ] |
| Official Symbol : | CCR7 |
| Synonyms : | CCR7; chemokine (C-C motif) receptor 7; CMKBR7, EBI1; C-C chemokine receptor type 7; BLR2; CD197; CDw197; CCR-7; CC-CKR-7; C-C CKR-7; MIP-3 beta receptor; CC chemokine receptor 7; chemokine (C-C) receptor 7; Epstein-Barr virus induced gene 1; EBV-induced G protein-coupled receptor 1; EBV-induced G-protein coupled receptor 1; Epstein-Barr virus induced G-protein coupled receptor; lymphocyte-specific G protein-coupled peptide receptor; epstein-Barr virus-induced G-protein coupled receptor 1; EBI1; CMKBR7; |
| Gene ID : | 1236 |
| mRNA Refseq : | NM_001838 |
| Protein Refseq : | NP_001829 |
| MIM : | 600242 |
| UniProt ID : | P32248 |
◆ Recombinant Protein
| Ccr7-906M | Recombinant Mouse Ccr7 Protein, MYC/DDK-tagged | +Inquiry |
| CCR7-3045H | Recombinant Human CCR7 Protein, MYC/DDK-tagged | +Inquiry |
| CCR7-0696H | Recombinant Human CCR7 Protein | +Inquiry |
| CCR7-4223C | Recombinant Chicken CCR7 | +Inquiry |
| CCR7-471H | Recombinant Human CCR7 | +Inquiry |
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◆ Assay kits
| Kit-1159 | CCR7 HEK 293 β-Arrestin GPCR Assay Kit | +Inquiry |
| Kit-1161 | cAMP CCR7 CHO-K1 GPCR Assay Kit | +Inquiry |
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