| Description : |
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Fc |
| Form : |
Lyophilized |
| Molecular Mass : |
62.4 kDa |
| Protein Length : |
375 |
| AA Sequence : |
MERASCLLLLLLPLVHVSATTPEPC ELDDEDFRCVCNFSEPQPDWSEAFQ CVSAVEVEIHAGGLNLEPFLKRVDA DADPRQYADTVKALRVRRLTVGAAQ VPAQLLVGALRVLAYSRLKELTLED LKITGTMPPLPLEATGLALSSLRLR NVSWATGRSWLAELQQWLKPGLKVL SIAQAHSPAFSCEQVRAFPALTSLD LSDNPGLGERGLMAALCPHKFPAIQ NLALRNTGMETPTGVCAALAAAGVQ PHSLDLSHNSLRATVNPSAPRCMWS SALNSLNLSFAGLEQVPKGLPAKLR VLDLSCNRLNRAPQPDELPEVDNLT LDGNPFLVPGTALPHEGSMNSGVVP ACARSTLSVGVSGTLVLLQGARGFA |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
