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Recombinant Human CD200 protein, hFc-tagged

Cat.No. : CD200-165H
Product Overview : Recombinant Human CD200 protein(P41217-1)(Gln31-Gly232), fused with C-terminal hFc tag, was expressed in HEK293.
Availability February 10, 2025
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Source : HEK293
Species : Human
Tag : C-hFc
Protein length : Gln31-Gly232
Form : Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.
Bio-activity : Immobilized Human CD200 R1, His Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Human CD200, hFc Tag with the EC50 of 0.77ng/ml determined by ELISA.
Molecular Mass : The protein has a predicted MW of 49.2 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
Endotoxin : Less than 1EU per μg by the LAL method.
Purity : > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Storage : Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Reconstitution : Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Gene Name : CD200 CD200 molecule [ Homo sapiens ]
Official Symbol : CD200
Synonyms : CD200; CD200 molecule; antigen identified by monoclonal MRC OX 2 , CD200 antigen , MOX1, MOX2; OX-2 membrane glycoprotein; MRC; OX 2; CD200 antigen; MRC OX-2 antigen; antigen identified by monoclonal MRC OX-2; MOX1; MOX2; OX-2;
Gene ID : 4345
mRNA Refseq : NM_001004196
Protein Refseq : NP_001004196
MIM : 155970
UniProt ID : P41217

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
08/01/2022

    Swift protein sequencing, helps identify unknown proteins.

    05/04/2022

      Great protein crystallization services, key for structural biology.

      05/02/2019

        Invaluable protein-protein interaction assays, integral for research.

        Q&As (7)

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        How does CD200 contribute to the regulation of bone marrow and hematopoietic stem cell niches? 10/04/2022

        CD200 regulates bone marrow and hematopoietic environments, supporting stem cell maintenance and differentiation.

        How does CD200 influence tumor immune evasion and the tumor microenvironment in cancer? 07/10/2021

        CD200 contributes to immune evasion in cancers, affecting tumor progression and response to immunotherapy.

        What role does CD200 play in the suppression of inflammatory responses in autoimmune diseases? 04/06/2021

        CD200 plays a role in suppressing inflammatory responses, which is crucial in autoimmune disease management.

        What are the effects of CD200 dysregulation on tissue graft rejection and transplant tolerance? 02/09/2019

        Dysregulation of CD200 affects tissue graft rejection, influencing transplant tolerance and success.

        How do alterations in CD200 expression impact the aging process and age-related immune changes? 09/17/2018

        Changes in CD200 expression impact the aging immune system, affecting age-related immune regulation and function.

        What is the impact of CD200 expression on neuroinflammatory processes and neurodegenerative diseases? 03/20/2018

        CD200 expression influences neuroinflammatory processes, potentially impacting neurodegenerative diseases.

        How does CD200 interact with its receptor CD200R, and what are the implications for immune regulation? 03/18/2018

        CD200 interacts with CD200R to modulate immune responses, promoting immune tolerance and reducing inflammation.

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