Recombinant Human CD200 protein, His-tagged
Cat.No. : | CD200-2059H |
Product Overview : | Recombinant Human CD200 protein (Gln31-Gly232) was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
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Species : | Human |
Source : | HEK293 |
Tag : | His |
ProteinLength : | Gln31-Gly232 |
Description : | CD200 is also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200/OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2/CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion. |
Predicted N Terminal : | Gln 31 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 23.3 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >98% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name | CD200 |
Official Symbol | CD200 |
Synonyms | MRC; MOX1; MOX2; OX-2 |
Gene ID | 4345 |
mRNA Refseq | NM_005944.7 |
Protein Refseq | NP_005935.4 |
MIM | 155970 |
UniProt ID | P41217 |
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Not For Human Consumption!
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