Recombinant Human CD200R1 Protein, Fc-tagged

• Cat.No.: CD200R1-347H
• Product Overview: Recombinant Human CD200R1, transcript variant 1, fused with Fc tag at C-terminal was expressed in HEK293 cells.

Specification

• Description: This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants.
• Source: HEK293 cells
• Tag: Fc
• Form: Lyophilized from a 0.2 µM filtered solution of PBS, pH 7.4
• Molecular Mass: 53.9kD
• AA Sequence: AAQPNNSLMLQTSKENHALASSSLC MDEKQITQNYSKVLAEVNTSWPVKM ATNAVLCCPPIALRNLIIITWEIIL RGQPSCTKAYKKETNETKETNCTDE RITWVSRPDQNSDLQIRTVAITHDG YYRCIMVTPDGNFHRGYHLQVLVTP EVTLFQNRNRTAVCKAVAGKPAAHI SWIPEGDCATKQEYWSNGTVTVKST CHWEVHNVSTVTCHVSHLTGNKSLY IELLPVPGAKKSAKLVDDIEGRMDE PKSCDKTHTCPPCPAPELLGGPSVF LFPPKPKDTLMISRTPEVTCVVVDV SHEDPEVKFNWYVDGVEVHNAKTKP REEQYNSTYRVVSVLTVLHQDWLNG KEYKCKVSNKALPAPIEKTISKAKG QPREPQVYTLPPSREEMTKNQVSLT CLVKGFYPSDIAVEWESNGQPENNY KTTPPVLDSDGSFFLYSKLTVDKSR WQQGNVFSCSVMHEALHNHYTQKSL SLSPGK
• Endotoxin: Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Gene Information

• Gene Name: CD200R1 CD200 receptor 1 [ Homo sapiens ]
• Official Symbol: CD200R1
• Synonyms: CD200R1; CD200 receptor 1; MOX2 receptor , MOX2R; cell surface glycoprotein CD200 receptor 1; CD200R; HCRTR2; OX2R; MOX2 receptor; CD200 cell surface glycoprotein receptor; cell surface glycoprotein OX2 receptor 1; cell surface glycoprotein receptor CD200; MOX2R
• Gene ID: 131450
• mRNA Refseq: NM_138806
• Protein Refseq: NP_620161
• MIM: 607546
• UniProt ID: Q8TD46