Recombinant Human CD276 Protein, C-Avi-His tagged, Biotinylated

• Cat.No.: CD276-02H
• Product Overview: Biotinylated Recombinant Human CD276/B7-H3 (C-Avi-His) is produced by Human Cells. The target gene encoding leu29-pro245 is expressed with a C-Avi-His tag.

Specification

• Species: Human
• Source: Human Cells
• Tag: Avi&His
• Protein Length: leu29-pro245
• Description: B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.
• Endotoxin: Less than 0.1 ng/μg (1 EU/μg)
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4
• Shipping: Ambient
• Conjugation: Biotin

Gene Information

• Gene Name: CD276 CD276 molecule [ Homo sapiens (human) ]
• Official Symbol: CD276
• Synonyms: B7-H3; CD276; B7 homolog 3
• Gene ID: 80381
• mRNA Refseq: NM_001024736
• Protein Refseq: NP_001019907
• MIM: 605715
• UniProt ID: Q5ZPR3