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Recombinant Human CD28 Protein

Cat.No. : CD28-0772H
Product Overview : Human CD28 full-length ORF (AAH93698.1) recombinant protein without tag.
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Description : The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]
Source : Wheat Germ
Species : Human
Form : Liquid
Molecular Mass : 25.1 kDa
AA Sequence : MLRLLLALNLFPSIQVTGNKILVKQ SPMLVAYDNAVNLSCKYSYNLFSRE FRASLHKGLDSAVEVCVVYGNYSQQ LQVYSKTGFNCDGKLGNESVTFYLQ NLYVNQTDIYFCKIEVMYPPPYLDN EKSNGTIIHVKGKHLCPSPLFPGPS KPFWVLVVVGGVLACYSLLVTVAFI IFWVRSKRSRLLHSDYMNMTPRRPG PTRKHYQPYAPPRDFAAYRS
Applications : Antibody Production
Functional Study
Compound Screening
Usage : Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 25 mM Tris-HCl of pH8.0 containing 2% glycerol.
Tag : Non
Gene Name : CD28 CD28 molecule [ Homo sapiens ]
Official Symbol : CD28
Synonyms : CD28; CD28 molecule; CD28 antigen (Tp44); T-cell-specific surface glycoprotein CD28; T cell specific surface glycoprotein; CD28 antigen; Tp44; MGC138290;
Gene ID : 940
mRNA Refseq : NM_001243077
Protein Refseq : NP_001230006
MIM : 186760
UniProt ID : P10747

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Customer Reviews (3)

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Reviews
08/24/2021

    Its unique characteristics contribute to obtaining clear and detailed structural information, enabling researchers to unravel the intricate complexities of protein interactions and conformational changes.

    08/24/2021

      Researchers can confidently rely on its capabilities to generate precise and significant results, enhancing the understanding of protein function and dynamics.

      08/06/2021

        the CD28 protein's outstanding performance in ELISA and its utility in protein electron microscopy structure analysis make it a highly recommended tool for researchers.

        Q&As (5)

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        Can CD28 protein be used for personalized medicine? 01/13/2023

        CD28 protein expression and function may be relevant for personalized treatment strategies in autoimmune diseases and cancer.

        What are the potential clinical applications of targeting CD28 protein? 05/18/2021

        Targeting CD28 protein may have therapeutic potential in treating autoimmune diseases, cancer immunotherapy, and organ transplantation.

        How does CD28 protein impact regulatory T cells (Tregs)? 06/21/2019

        CD28 signaling is important for the function and maintenance of regulatory T cells, which play a role in immune tolerance and suppression of autoimmunity.

        How does CD28 protein impact cancer immunotherapy? 11/26/2018

        CD28 protein is involved in enhancing the anti-tumor immune response, making it a potential target for cancer immunotherapy.

        Are there any approved therapies targeting CD28 protein? 05/27/2017

        Currently, there are no FDA-approved therapies specifically targeting CD28 protein, but research is ongoing in this area.

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