| Cat.No. : |
CD28-32H
Optional Service: Optional requirements on this protein
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| Product Overview : |
Human CD28-muIg fusion protein was Protein A purified from (low FBS containing) tissue culture supernatant of CHO transfectants, and reacted with NHS-Biotin. Unconjugated Biotin was removed from conjugate by diafiltration. A soluble fusion protein consisting of the extracellular (134aa) domain of human CD28 fused to murine IgG2a Fc (233aa). |
| Description : |
Human CD28 is an important costimulatory molecule found on all CD4+ T cells and on about half of the CD8+T cells. T cell activities attributed to CD28 include, prevention of anergy, induction of cytokine gene transcription, stabilization of cytokine mRNAs and activation of CD8+ cytotoxic T lymphocytes. The ligands for CD28, identified as CD80 (B7-1) and CD86 (B7-2), are immunoglobulin superfamily monomeric transmembrane glycoproteins of 60 kd and 80 kd, respectively. |
| Source : |
CHO |
| Species : |
Human |
| Bio-activity : |
CD28-muIg/Biotin activity was assessed in EIA utilizing GAM-captured Recombinant CD80-muIg, and Streptavidin/HRP as a detector. In this format, the fusion protein was detectable at 100 ng/ml. |
| Notes : |
Research use only. Not for use in Diagnostic procedures. |
| Stability : |
Product should retain activity for at least 12 months after shipping date when stored as recommended. |
| Storage : |
Store at 2 - 5 centigrade. Freeze/Thawing is not recommended. |
| Concentration : |
0.5 mg/mL |
| Storage Buffer : |
50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.