Recombinant Human CD3E&CD3G protein, His-tagged

• Cat.No.: CD3E&CD3G-794H
• Product Overview: Human CD3 epsilon & CD3 gamma Heterodimer Protein is expressed from mammalian with a His Tag at the C-terminal. It contains Asp23-Glu120 (CD3E) & Gln23-Gln106 (CD3G).

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: Asp23-Glu120 (CD3E) & Gln23-Gln106 (CD3G)
• Description: T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a calculated MW of 16.4 kDa (CD3E) and13.9kDa (CD3G). As a result of glycosylation, the protein migrates to 25-30 kDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 0.05EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: CD3E&CD3G
• Official Symbol: CD3E&CD3G
• Synonyms: CD3; CD3D; CD3-DELTA; T3D; CD3G
• Gene ID: 916 & 917
• mRNA Refseq: NM_000733.4 & NM_000073.3
• Protein Refseq: NP_000724.1 & NP_000064.1
• MIM: 186830 & 186740
• UniProt ID: P07766 & P09693