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Recombinant Human CD40 Protein, His & Avi-tagged, Biotinylated

Cat.No.: CD40-2222H
Product Overview: Biotinylated Recombinant Human CD40 Protein (Glu 21 - Arg 193) (AAH12419.1), fused with an Avi tag at the C-terminus, followed by a polyhistidine tag, was expressed in HEK293.
Source: HEK293
Species: Human
Tag : His & Avi
Predicted N Terminal: Glu 21
Form: Lyophilized from sterile PBS, pH7.4, 10% trehalose.
Molecular Mass: Recombinant Human CD40 Protein has a calculated MW of 21.8 kDa. The protein migrates as 30-35 kDa on a SDS-PAGE gel under reducing (R) condition due to glycosylation.
Protein length: Glu 21 - Arg 193
Endotoxin: Less than 1.0 EU per μg by the LAL method.
Purity: >95% as determined by SDS-PAGE.
Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name: CD40 CD40 molecule, TNF receptor superfamily member 5 [ Homo sapiens ]
Official Symbol: CD40
Synonyms: CD40; CD40 molecule, TNF receptor superfamily member 5; TNFRSF5, tumor necrosis factor receptor superfamily, member 5; tumor necrosis factor receptor superfamily member 5; Bp50; p50; CD40L receptor; CD40 type II isoform; B cell-associated molecule; B cell surface antigen CD40; B-cell surface antigen CD40; CD40 antigen (TNF receptor superfamily member 5); tumor necrosis factor receptor superfamily, member 5; nerve growth factor receptor-related B-lymphocyte activation molecule; CDW40; TNFRSF5; MGC9013;
Gene ID: 958
mRNA Refseq: NM_001250
Protein Refseq: NP_001241
MIM: 109535
UniProt ID: P25942
Chromosome Location: 20q12-q13.2
Pathway: Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem;
Function: enzyme binding; protein binding; receptor activity; signal transducer activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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