Recombinant Human CD48 protein, His-tagged
Cat.No. : | CD48-654H |
Product Overview : | Recombinant Human CD48 (Gln27-Ser220) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
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Description : | CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Gln27 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 23.2 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Gln27-Ser220 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | CD48 |
Official Symbol : | CD48 |
Synonyms : | CD48; CD48 molecule; BCM1, CD48 antigen (B cell membrane protein) , CD48 molecule; CD48 antigen; BLAST; hCD48; mCD48; SLAMF2; TCT.1; BCM1 surface antigen; leukocyte antigen MEM-102; B-lymphocyte activation marker BLAST-1; CD48 antigen (B-cell membrane protein); BCM1; BLAST1; MEM-102 |
Gene ID : | 962 |
mRNA Refseq : | NM_001256030 |
Protein Refseq : | NP_001242959 |
MIM : | 109530 |
UniProt ID : | P09326 |
Products Types
◆ Recombinant Protein | ||
CD48-34H | Recombinant Human CD48 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
CD48-0828H | Recombinant Human CD48 Protein, GST-Tagged | +Inquiry |
CD48-2042H | Recombinant Human CD48 Protein, Fc/His-tagged | +Inquiry |
CD48-720M | Recombinant Mouse CD48 Protein | +Inquiry |
Cd48-8762R | Recombinant Rat Cd48 protein(Met1-Arg216), hFc-tagged | +Inquiry |
◆ Lysates | ||
CD48-3044HCL | Recombinant Human CD48 cell lysate | +Inquiry |
CD48-2468MCL | Recombinant Mouse CD48 cell lysate | +Inquiry |
CD48-1258RCL | Recombinant Rat CD48 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThere is currently no treatment that directly regulates CD48 protein expression levels. However, by regulating the function of the immune system, the expression level of CD48 protein can be indirectly affected to treat some diseases.
Expression level of CD48 protein is associated with the prognosis of certain tumors. In some cancers, high levels of CD48 protein expression may predict a poor prognosis.
CD48 protein is an important molecule in the immune system that is involved in the activation and differentiation of lymphocytes and phagocytes, as well as inflammation and tissue repair. Its expression levels may affect the function of the immune system.
Studies have shown that the expression level of CD48 protein may affect the effectiveness of vaccination. In some cases, high levels of CD48 protein expression may suppress the immune response, thus affecting the effectiveness of vaccination.
Yes, the CD48 protein can be used as a biomarker for some tumors. Studies have shown that in some cancers, high levels of CD48 protein expression may predict tumor growth and metastasis.
Studies have shown that the expression level of CD48 protein may be associated with the occurrence and progression of certain diseases. For example, in some cancers, the expression level of the CD48 protein may affect the growth and metastasis of the tumor.
Customer Reviews (3)
Write a reviewThe anti-interference ability in Western blot is very strong, which can effectively resist the influence of endogenous interference factors.
High safety, high expression level, ideal for laboratory and practical applications.
Low preparation cost, high cost performance, saving funds, very suitable for our research.
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