Recombinant Human CD5 Protein (Met1-Pro372), HlgG1 Fc-tagged

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Recombinant Human CD5 Protein (Met1-Pro372), HlgG1 Fc-tagged

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Cat.No. : CD5-1093H
Product Overview : Recombinant Human CD5 Protein (NP_055022.2) (Met1-Pro372) was produced by HEK293 Cells expression system. This protein was expressed with the Fc region of human IgG1 at the C-terminus.
Description : The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 32 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD5 is a member of the CD system. CD5 was found to be widely distributed in T-cells and B1 cells which is a subset of IgM-secreting B cells. CD5 also was found expressed in small lymphocytic lymphoma, hairy cell leukaemia and mantle cell lymphoma cells. CD5 serves to weaken the activating stimulus from the BCR so that the B1 cells can only reflect to the very strong stimuli but not the normal tissue proteins.
Source : HEK293
Species : Human
Tag : HlgG1 Fc
Predicted N Terminal : Arg 25
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The recombinant human CD5 consists of 586 amino acids and predicts a molecular mass of 65.4 kDa.
Protein length : Met1-Pro372
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 90 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70 centigrade.
Storage : Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Shipping : In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Gene Name : CD5 CD5 molecule [ Homo sapiens ]
Official Symbol : CD5
Synonyms : CD5; CD5 molecule; CD5 antigen (p56 62) , LEU1; LEU1;
Gene ID : 921
mRNA Refseq : NM_014207
Protein Refseq : NP_055022
MIM : 153340
UniProt ID : P06127

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