Recombinant Mouse Cd5 protein, His-tagged

• Cat.No.: Cd5-2277M
• Product Overview: Recombinant Mouse Cd5 protein(P13379)(Ser25-Pro371), fused with C-terminal His tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Mouse
• Tag: C-His
• Protein length: Ser25-Pro371
• Form: Supplied as 0.22μm filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 38.9 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
• Endotoxin: Less than 1EU per μg by the LAL method.
• Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
• Storage: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please do not repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: Cd5 CD5 antigen [ Mus musculus ]
• Official Symbol: Cd5
• Synonyms: CD5; CD5 antigen; T-cell surface glycoprotein CD5; lymphocyte antigen 1; Ly-1; Ly-A; Ly-12; Lyt-1
• Gene ID: 12507
• mRNA Refseq: NM_007650
• Protein Refseq: NP_031676

Reviews

08/18/2022

The stability of CD5 is very good, and even if it is stored for a long time, it will not affect its performance.

12/20/2021

I have recommended it to other students, the price is affordable, the operation is convenient, and the effect is good.

11/28/2020

I'm very happy with the results, the stability is strong.

Q&As

What is the interaction between CD5 and other biomolecules?

There are interactions between CD5 and other biomolecules. For example, it binds to antigens and antibodies and participates in the activation and differentiation of immune cells, and also binds to other signal transduction molecules and participates in cell signal transduction.

Which biomolecules can be used as molecular markers for CD5?

Certain biomolecules can be used as molecular markers of CD5, including CD5 antigens detected on the surface of lymphocytes, as well as related proteins and genes that interact with CD5. These markers can be used for early diagnosis of diseases, prognosis judgment, or monitoring the effectiveness of treatment.

How can the efficacy and safety of treatments for CD5 be assessed?

Assessing the efficacy and safety of treatments targeting CD5 requires clinical trials and drug monitoring. The effectiveness of the treatment was evaluated by designing a rigorous clinical trial protocol that compared the disease remission rate, symptom improvement, and quality of life improvement between the treatment and control groups. At the same time, drug monitoring is used to monitor the safety and efficacy of drugs in actual use, adjust treatment regimens in a timely manner, maximize the efficacy of drugs and reduce the risk of side effects.

What is the structure of CD5?

CD5 has a typical immunoglobulin superfamily domain, which is a single-stranded transmembrane glycoprotein that is distributed in an asymmetrical manner across the cell membrane. This structure allows it to bind to antigens and antibodies and participate in the immune response.

What diseases are CD5 associated with?

CD5 has been linked to a number of immune system-related diseases. For example, certain autoimmune diseases, allergic reactions, transplant rejection, etc. In addition, CD5 has been implicated in the development and progression of certain tumors.

How is the therapeutic strategy of CD5 evaluated?

Treatment strategies for CD5 include inhibition of its activity, regulation of its expression, and gene therapy. For example, the development of antibody drugs or small molecule inhibitors against CD5 to inhibit its overactivation in the immune response, or the regulation of CD5 expression through gene knockout or overexpression techniques.