Recombinant Human CD55 Protein, Fc-tagged, FITC conjugated
Cat.No. : | CD55-64HF |
Product Overview : | FITC conjugated recombinant human CD55 precursor (NP_000565.1) (Met 1-Ser 353), fused with the C-terminal Fc region of human IgG1, was produced in Human Cell. |
Availability | July 26, 2024 |
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Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized |
Molecular Mass : | The recombinant human CD55/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 557 amino acids and has a predicted molecular mass of 61.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhCD55/Fc monomer is approximately 95-105 kDa due to glycosylation. |
Protein length : | 557 |
Endotoxin : | < 1.0 EU/ μg of the protein as determined by the LAL method. |
Characteristic : | Disulfide-linked homodimer Labeled with FITC via amines Excitation source: 488 nm spectral line, argon-ion laser Excitation Wavelength: 488 nm Emission Wavelength: 535 nm |
Stability : | Samples are stable for up to 12 months from date of receipt at -70 centigrade. |
Storage : | Store it under sterile conditions at -20 to -70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Lyophilized from sterile PBS, pH 7.4 |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
Gene Name : | CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) [ Homo sapiens ] |
Official Symbol : | CD55 |
Gene ID : | 1604 |
mRNA Refseq : | NM_000574 |
Protein Refseq : | NP_000565 |
MIM : | 125240 |
UniProt ID : | P08174 |
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◆ Lysates | ||
CD55-2531HCL | Recombinant Human CD55 cell lysate | +Inquiry |
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CD55-1669MCL | Recombinant Mouse CD55 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewEfficient shipping and exceptional product quality. This company knows how to serve its customers.
Consistency is key in research, and this product delivers that every time.
We've tried various proteins, but this one stands out for its purity and performance.
Q&As (5)
Ask a questionGenetic variations in CD55 may influence susceptibility to complement-mediated disorders by affecting the protein's ability to regulate complement activation. This can lead to conditions like paroxysmal nocturnal hemoglobinuria (PNH).
CD55 has immunomodulatory functions beyond complement regulation, influencing T cell responses and contributing to the maintenance of immune tolerance.
CD55 protects cells from complement-mediated lysis by preventing the formation of membrane attack complexes. This contributes to immune evasion by pathogens and self-cells alike.
CD55 consists of extracellular domains responsible for interactions with complement proteins, particularly C3b and C4b. These interactions prevent the formation of membrane attack complexes on host cells.
CD55 dysregulation is associated with autoimmune disorders, where it may contribute to immune system overactivity. Additionally, some pathogens exploit CD55 to evade host immune responses.
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